Composite ePTFE/textile prosthesis

• US 7,828,833 B2
• Filed: 06/11/2002
• Issued: 11/09/2010
• Est. Priority Date: 06/11/2001
• Status: Expired due to Fees

• Current Assignee: Lifeshield Sciences LLC (Acacia Research Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Chouinard, Paul, Haverkost, Pat, Sowinski, Krzysztof, Rakos, Ronald
• Primary Examiner(s): McDermott; Corrine M
• Assistant Examiner(s): Prone; Christopher D
• Application Number:
  US10/166,842
• Publication Number:
  US 20030139806A1
• Time in Patent Office: 3,073 Days
• Field of Search: 623/1.1, 623/1.13, 623/1.15, 623/1.39, 623/1.44
• US Class Current: 623/1.13
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61L 27/16 obtained by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/48 with macromolecular fillers
• CPC Class Codes: A61L 27/50 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61L 27/507 for artificial blood vessels apparatus for applying cells on a blood vessel prosthesis A61F2/062
• CPC Class Codes: A61L 31/048 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/129 containing macromolecular fillers
• CPC Class Codes: C08L 27/18 Homopolymers or copolymers or tetrafluoroethene

Abstract

A composite intraluminal prosthesis which is preferably used as a vascular prosthesis includes a layer of ePTFE and a layer of textile material which are secured together by an elastomeric bonding agent. The ePTFE layer includes a porous microstructure defined by nodes interconnected by fibrils. The adhesive bonding agent is preferably applied in solution so that the bonding agent enters the pores of the microstructure of the ePTFE. This helps secure the textile layer to the ePTFE layer.

Claims

1. A composite multilayer implantable structure comprising:

a first inner tubular layer and second outer tubular layer formed of expanded polytetrafluoroethyene having a porous microstructure defined by nodes interconnected by fibrils, said first and second layers each seamless and substantially fluid-tight, said first and second layers each formed from a green fluoropolymer tube characterized by a generally uniform thickness being in the range of up to about 250 μ

m, said first and second layers having a support structure positioned there between, wherein said first layer is a blood contacting layer;

a third tubular layer formed of textile material circumferentially disposed exteriorly to said first and second layers, wherein said third tubular layer is a tissue contacting layer; and

an elastomeric bonding agent layer with a Shore Hardness of about 75 to 85A, said layer consisting essentially of a material selected from the group consisting of polycarbonate urethanes, styrene-isobutylene block copolymers, and combinations thereof, applied to cover one of said second layer or third layer and disposed within the pores of said microstructure to seal punctures, and for securing said second layer to said third layer;

wherein said first, second, and third tubular layers form an elongate vascular graft.

2. A composite structure of claim 1 wherein said bonding agent is applied to one surface of said second layer.

3. A composite structure of claim 2 wherein said third layer is placed in contact with said one surface of said second layer.

4. A composite structure of claim 1 wherein said bonding agent is applied to a surface of said third textile layer.

5. A composite structure of claim 1 wherein said third layer comprises a textile pattern selected from the group comprising knits, weaves, stretch-knits, braids, any non-woven process, and combinations thereof.

6. A composite structure of claim 1 wherein said support structure comprises a stent.

7. A composite structure of claim 1 wherein said graft includes a plurality of longitudinally spaced crimps therealong.

8. A composite structure of claim 1 wherein said graft is helically wrapped with a monofilament externally therearound.

9. A composite structure of claim 8 wherein said monofilament comprises polypropylene.

10. A composite structure of claim 9 wherein said monofilament is attached by heat bonding.

11. A composite structure of claim 8 wherein said graft includes an external support coil helically positioned thereover.

12. A composite structure of claim 1 wherein said elastomeric bonding agent is applied to said second layer in solution.

13. A composite structure of claim 12 wherein said solution includes dimethylacetamide.

14. A composite structure of claim 1 further comprising a fourth tubular layer formed of textile material circumferentially disposed interiorly to said first and second layers;

and an elastomeric bonding agent applied to one of said first layer or said fourth layer and disposed within the pores of said microstructure for securing said first layer to said fourth layer.

15. A composite structure of claim 1, wherein the first inner tubular layer and the second outer tubular layer are each a discrete tubular layer.