Methods and compositions to improve germ cell and embryo survival and function
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First Claim
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1. A nonspermicidal lubricant comprising a balanced salt solution, a nonspermicidal lubricious compound which is able to lubricate vaginal mucosa, and arabinogalactan.
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Abstract
Sperm, oocyte, and embryo survival and function is improved in vivo or in vitro by the use of a polysaccharide containing arabinose, galactose and/or hexuronic acid. In particular, a nonspermicidal lubricant containing such a polysaccharide (e.g., gum arabic, pectin, or galacturonic acid) increases the fertilization potential of the sperm during coitus, artificial insemination or sperm collection. Similarly, a freezing medium containing a polysaccharide containing arabinose, galactose and/or hexuronic acid enhances sperm, oocyte, or embryo viability.
18 Citations
2 Claims
- 1. A nonspermicidal lubricant comprising a balanced salt solution, a nonspermicidal lubricious compound which is able to lubricate vaginal mucosa, and arabinogalactan.
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Litigation Data
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Current AssigneeBio-Origyn LLC
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Original AssigneeBio-Origyn LLC
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InventorsOliver, Sylvia Adams, Ellington, Joanna E
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Primary Examiner(s)Afremova; Vera
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Application NumberUS10/431,634Publication NumberTime in Patent Office2,757 DaysField of Search424/430US Class Current514/54CPC Class CodesA01N 1/021 Preservation or perfusion m...A01N 1/0221 Freeze-process protecting a...A61K 35/52 Sperm; Prostate; Seminal fl...A61P 15/00 Drugs for genital or sexual...C12N 2500/60 Buffer, e.g. pH regulation,...C12N 5/061 Sperm cells, spermatogonia
