Calcium carbonate granulation

  • US 7,850,988 B2
  • Filed: 10/25/2006
  • Issued: 12/14/2010
  • Est. Priority Date: 07/31/2003
  • Status: Active Grant
First Claim
Patent Images

1. A calcium carbonate granulation for pharmaceutical or nutraceutical tabletting comprising:

  • (i) USP or food grade calcium carbonate powder having a median particle diameter of about 10 to about 12 μ

    m;

    (ii) one or more excipients selected from the group consisting of diluents, binders, glidants, lubricants, disintegrants, colors, flavors, sweeteners, solubility retarding agents, and combinations thereof; and

    (iii) less than about 1% by weight water;

    said granulation having a tap density between about 0.9 and about 2.0 g/cm3, said granulation being free flowing and having sufficient cohesive properties for compression into tablets.

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