Oxidation resistant indicator molecules
First Claim
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1. A method for using a molecule in oxidative conditions, which comprises:
- a) obtaining a molecule having an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation resistance as compared to a corresponding molecule without the one or more electron withdrawing groups; and
b) subjecting the molecule having the one or more electron withdrawing groups to oxidative conditions.
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Abstract
Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation resistance as compared to a corresponding molecule without the one or more electron withdrawing groups.
16 Citations
28 Claims
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1. A method for using a molecule in oxidative conditions, which comprises:
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a) obtaining a molecule having an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation resistance as compared to a corresponding molecule without the one or more electron withdrawing groups; and b) subjecting the molecule having the one or more electron withdrawing groups to oxidative conditions. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A method for detecting the presence or concentration of an analyte in a sample in an oxidative environment, said method comprising:
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a) exposing the sample to an indicator molecule having a detectable quality that changes when the indicator molecule is exposed to the analyte, said molecule comprising an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the indicator molecule has enhanced oxidation resistance as compared to the corresponding molecule without the one or more electron withdrawing groups; and b) measuring any change in said detectable quality to thereby determine the presence or concentration of said analyte in said sample. - View Dependent Claims (9, 10, 11, 12)
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- 13. A compound having the following structure:
- 17. A compound having the following structure:
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20. A method for the production of an indicator macromolecule for detecting the presence or concentration of an analyte in an oxidative environment, said method comprising copolymerizing:
a) one or more indicator component monomers which individually are not sufficiently water soluble to permit their use in an aqueous environment for detecting the presence or concentration of said analyte, wherein the indicator component monomer comprises compound having the following structure; - View Dependent Claims (21, 22, 23)
- 24. A compound having the following structure:
- 27. A compound having the following structure:
Specification