Closed-loop therapy adjustment

• US 7,853,322 B2
• Filed: 04/28/2006
• Issued: 12/14/2010
• Est. Priority Date: 12/02/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Miesel, Keith A., Bourget, Duane
• Primary Examiner(s): Bockelman; Mark W
• Assistant Examiner(s): Dinga; Roland
• Application Number:
  US11/414,625
• Publication Number:
  US 20070129774A1
• Time in Patent Office: 1,691 Days
• Field of Search: 607/17, 607/30, 607/62, 607/19, 607/27, 607/46, 607/48, 600/481, 600/529, 600/544, 600/546
• US Class Current: 607/2
• CPC Class Codes: A61N 1/36031 using physiological parameters for adjustment
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: A61N 1/37252 Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data

Abstract

Techniques for detecting a value of a sensed patient parameter, and automatically delivering therapy to a patient according to therapy information previously associated with the detected value, are described. In exemplary embodiments, a medical device receives a therapy adjustment from the patient. In response to the adjustment, the medical device associates a sensed value of a patient parameter with therapy information determined based on the adjustment. Whenever the parameter value is subsequently detected, the medical device delivers therapy according to the associated therapy information. In this manner, the medical device may “learn” to automatically adjust therapy in the manner desired by the patient as the sensed parameter of the patient changes. Exemplary patient parameters that may be sensed for performance of the described techniques include posture, activity, heart rate, electromyography (EMG), an electroencephalogram (EEG), an electrocardiogram (ECG), temperature, respiration rate, and pH.

Claims

1. A method comprising:

sensing a parameter of a patient via a sensor; and

,

using one or more processors;

receiving a therapy adjustment from the patient via a user interface, wherein the therapy adjustment received from the patient comprises an adjustment of a value of at least one parameter of a therapy delivered by a medical device to the patient;

determining therapy information based on the therapy adjustment;

detecting a value of the sensed parameter in response to the receipt of the therapy adjustment from the patient;

automatically associating the value of the sensed parameter with the therapy information in response to receiving the therapy adjustment;

subsequently detecting the value of the sensed parameter via the sensor; and

automatically delivering therapy to the patient via the medical device according to the therapy information associated with the value in response to the subsequent detection.

2. The method of claim 1, further comprising:

receiving, using the one or more processors, one of a plurality of therapy adjustments from the patient whenever the patient adjusts the therapy; and

using the one or more processors, for each of the therapy adjustments, determining respective therapy information based on the therapy adjustment, and automatically associating the respective therapy information with a respective value of the sensed parameter detected in response to receipt of the therapy adjustment in response to receiving the therapy adjustment.

3. The method of claim 2, wherein each of the therapy adjustments comprises one or more commands from the patient.

4. The method of claim 1, wherein the sensed parameter comprises at least one of posture, activity, heart rate, electromyogram (EMG), an electroencephalogram (EEG), an electrocardiogram (ECG), temperature, respiration rate, or pH.

5. The method of claim 1, wherein sensing the parameter comprises sensing a plurality of parameters of the patient, automatically associating the value of the sensed parameter with the therapy information comprises automatically associating a respective value for each of the plurality of parameters with the therapy information, and subsequently detecting the value of the sensed parameter comprises subsequently detecting the respective values in combination.

6. The method of claim 1, further comprising maintaining a data structure via the one or more processors, wherein associating the value of the sensed parameter with the therapy information comprises storing the associated parameter value and the therapy information as a record within the data structure.

7. The method of claim 6, wherein storing the associated parameter value and the therapy information as a record comprises:

determining whether any of a plurality of existing records of the data structure includes the parameter value; and

updating one of the plurality of existing records based on the therapy information when the existing record includes the parameter value.

8. The method of claim 6, wherein storing the associated parameter value and therapy information as a record comprises:

determining whether any of a plurality of existing records of the data structure includes the parameter value; and

creating a new record that includes the parameter value and the therapy information when the plurality of existing records of the data structure do not include the parameter value.

9. The method of claim 1, further comprising:

receiving an input to stop delivery of the therapy according to the therapy information associated with the parameter value; and

removing the association of the therapy information with the parameter value in response to the input.

10. The method of claim 9, further comprising associating, using the one or more processors, the parameter value with predetermined default therapy information.

11. The method of claim 1, further comprising:

detecting another value of the sensed patient parameter via the sensor;

determining, using the one or more processors, that the detected another value is not presently associated with therapy information; and

automatically associating, using the one or more processors, the detected another value with current therapy parameter values based on the determination.

12. The method of claim 1, wherein therapy comprises stimulation and the therapy information comprises a plurality of stimulation parameters.

13. The method of claim 12, wherein the plurality of stimulation parameters comprise an electrode configuration, a pulse rate, a pulse width, and an amplitude.

14. A system comprising:

a medical device configured to deliver a therapy to a patient;

a sensor configured to sense parameter of the patient;

a user interface; and

a processor configured to;

receive a therapy adjustment from the patient via the user interface, wherein the therapy adjustment received from the patient comprises an adjustment of a value of at least one parameter of the therapy delivered by the medical device to the patient,

determine therapy information based on the therapy adjustment,

detect a value of the sensed parameter in response to the receipt of the therapy adjustment from the patient,

automatically associate the value of the sensed parameter detected via the sensor in response to the receipt of the therapy adjustment with the therapy information in response to receiving the therapy adjustment,

subsequently detect the value of the sensed parameter via the sensor, and

automatically control the medical device to deliver therapy to the patient according to the therapy information associated with the value in response to the subsequent detection.

15. The system of claim 14, wherein the processor receives one of a plurality of therapy adjustments from the patient whenever the patient adjusts the therapy via the user interface, and, for each of the therapy adjustments, determines respective therapy information based on the therapy adjustment, and automatically associates the respective therapy information with a respective value of the sensed parameter detected in response to receipt of the therapy adjustment in response to receiving the therapy adjustment.

16. The system of claim 15, wherein each of the therapy adjustments comprises one or more commands from the patient.

17. The system of claim 14, wherein the sensed parameter comprises at least one of posture, activity, heart rate, electromyogram (EMG), an electroencephalogram (EEG), an electrocardiogram (ECG), temperature, respiration rate, or pH.

18. The system of claim 14,

wherein the sensor comprises one or more sensors that sense a plurality of parameters of the patient, and

wherein the processor automatically associates a respective value for each of the plurality of parameters with the therapy information, subsequently detects the respective values in combination, and automatically controls the medical device to deliver therapy to the patient according to the therapy information associated with the value in response to the subsequent detection.

19. The system of claim 14, further comprising a memory, wherein the processor maintains a data structure within the memory, and stores the associated parameter value and the therapy information as a record within the data structure.

20. The system of claim 19, wherein the processor determines whether any of a plurality of existing records of the data structure includes the parameter value, and updates one of the plurality of existing records based on the therapy information when the existing record includes the parameter value.

21. The system of claim 19, wherein the processor determines whether any of a plurality of existing records of the data structure includes the parameter value, and creates a new record that includes the parameter value and the therapy information when the plurality of existing records of the data structure do not include the parameter value.

22. The system of claim 14, wherein the processor receives an input to stop delivery of the therapy according to the therapy information associated with the parameter value via the user interface, and removes the association of the therapy information with the parameter value in response to the input.

23. The system of claim 22, wherein the processor associates the parameter value with predetermined default therapy information in response to the input.

24. The system of claim 14, wherein the processor detects another value of the sensed patient parameter via the sensor, determines that the detected another value is not presently associated with therapy information, and automatically associates the detected value with current therapy parameter values based on the determination.

25. The system of claim 14, wherein medical device delivers stimulation, and the therapy information comprises a plurality of stimulation parameters.

26. The system of claim 25, wherein the plurality of stimulation parameters comprise an electrode configuration, a pulse rate, a pulse width, and an amplitude.

27. The system of claim 14, wherein:

the medical device comprises the processor; and

the medical device one of comprises the sensor or is coupled to the sensor.

28. The system of claim 14, wherein the medical device is implantable within the patient.

29. The system of claim 14, wherein medical device delivers pain therapy to the patient.

30. The system of claim 14, wherein the medical device delivers spinal cord stimulation therapy to the patient.

43. The system of claim 14, wherein the therapy comprises electrical stimulation therapy, and wherein the at least one parameter of the therapy comprises at least one stimulation parameter.

44. The system of claim 43, wherein the at least one stimulation parameter includes at least one of amplitude, pulse width, pulse rate, or electrode configuration.

45. The system of claim 14, wherein the processor receives the therapy adjustment from the patient by at least receiving an indication of a therapy program selected by the patient via the user interface.

31. A system comprising:

means for receiving a therapy adjustment from a patient, the therapy adjustment comprising an adjustment of a value of at least one parameter of the therapy delivered by a medical device to the patient;

means for detecting a value of a sensed parameter of the patient in response to receipt of the therapy adjustment by the means for receiving the therapy adjustment;

means for determining therapy information based on the therapy adjustment;

means for automatically associating the value of the sensed parameter detected by the means for detecting in response to the receipt of the therapy adjustment with the therapy information in response to receiving the therapy adjustment;

means for subsequently detecting the value of the sensed parameter; and

means for automatically delivering therapy to the patient according to the therapy information associated with the value in response to the subsequent detection.

32. The system of claim 31, wherein the means for receiving comprises means for receiving one of a plurality of therapy adjustments from the patient whenever the patient adjusts the therapy, the means for determining therapy information comprises means for determining respective therapy information for each of the therapy adjustments based on the therapy adjustment, and the means for automatically associating comprises means for automatically associating the respective therapy information with a respective value of the sensed parameter for each of the therapy adjustments in response to receiving the therapy adjustment.

33. The system of claim 31, wherein the sensed parameter comprises posture, activity, heart rate, electromyogram (EMG), an electroencephalogram (EEG), an electrocardiogram (ECG), temperature, respiration rate, or pH.

34. The system of claim 31, wherein the therapy comprises electrical stimulation, and the therapy information comprises an electrode configuration, a pulse rate, a pulse width, and an amplitude.

46. The system of claim 31, wherein the therapy comprises electrical stimulation therapy, and wherein the at least one parameter of the therapy comprises at least one stimulation parameter.

47. The system of claim 46, wherein the at least one stimulation parameter includes at least one of amplitude, pulse width, pulse rate, or electrode configuration.

48. The system of claim 31, wherein the means for receiving a therapy adjustment from a patient comprises means for receiving an indication of a therapy program selected by the patient.

35. A system comprising:

a medical device configured to deliver therapy to a patient;

a user interface;

a sensor configured to sense a posture of the patient; and

a processor configured to;

receive a therapy adjustment from a patient via the user interface, wherein the therapy adjustment comprises an adjustment to a value of at least one parameter of the therapy delivered by the medical device to the patient,

determine therapy information based on the therapy adjustment,

detect the posture of the patient in response to receipt of the therapy adjustment,

automatically associate the posture of the patient detected via the sensor in response to the receipt of the therapy adjustment with the therapy information in response to receiving the therapy adjustment,

subsequently detect the posture via the sensor, and

automatically control the medical device to deliver therapy to the patient according to the therapy information associated with the posture in response to the subsequent detection of the posture.

36. The system of claim 35, wherein the processor receives one of a plurality of therapy adjustments from the patient whenever the patient adjusts the therapy via the user interface, and, for each of the therapy adjustments, determines respective therapy information based on the therapy adjustment, and automatically associates the respective therapy information with a respective posture of the patient detected when the therapy adjustment is received in response to receiving the therapy adjustment.

37. The system of claim 35, further comprising a memory, wherein the processor is configured to maintain a data structure within the memory, and store the associated posture and the therapy information as a record within the data structure.

38. The system of claim 37, wherein the processor is configured to determine whether any of a plurality of existing records of the data structure includes the posture, and update one of the plurality of existing records based on the therapy information when the existing record includes the posture.

39. The system of claim 37, wherein the processor is configured to determine whether any of a plurality of existing records of the data structure includes the posture, and create a new record that includes the posture and the therapy information when the plurality of existing records of the data structure do not include the posture.

40. The system of claim 35, wherein the processor is configured to detect another postures of the patient via the sensor, determine that the detected another posture is not presently associated with therapy information, and automatically associate the detected another posture with current therapy parameter values based on the determination.

41. The system of claim 35, wherein medical device is configured to deliver stimulation to the patient, and the therapy information comprises a plurality of stimulation parameters.

42. The system of claim 41, wherein the plurality of stimulation parameters comprise an electrode configuration, a pulse rate, a pulse width, and an amplitude.

49. The system of claim 35, wherein the therapy comprises electrical stimulation therapy, and wherein the at least one parameter of the therapy comprises at least one stimulation parameter.

50. The system of claim 49, wherein the at least one stimulation parameter includes at least one of amplitude, pulse width, pulse rate, or electrode configuration.

51. The system of claim 35, wherein the processor receives the therapy adjustment from the patient by at least receiving an indication of a therapy program selected by the patient via the user interface.