Cardiac-valve prosthesis
First Claim
1. A cardiac valve prosthesis adapted for implantation at an implantation site of a patient, the implantation site having an annulus, a plurality of Valsalva sinuses, coronary ostia, and a vessel wall distal to the Valsalva sinuses, the prosthesis having a principal axis extending longitudinally therethrough and comprising:
- an armature adapted for delivery in a radially collapsed configuration and deployment in a radially expanded configuration, the armature defining a lumen for passage of blood flow and comprising;
first and second annular elements positioned about the principal axis, the first annular element adapted to engage a wall of the annulus proximal to the Valsalva sinus and the second annular element adapted to engage the vessel wall distal to the Valsalva sinus;
a plurality of anchor members extending from the first annular element to the second annular element, each anchor member arching radially outward with respect to the annular elements such that the anchor member is adapted to extend into and generally conform to a respective one of the Valsalva sinuses between the first and second annular elements to enable anchorage of the prosthesis at the implantation site when the cardiac valve prosthesis is deployed at the implantation site with the armature in the radially expanded configuration; and
a plurality of valve support members connected to and extending between the first and second annular elements and oriented generally parallel to the principal axis of the prosthesis, wherein each of the valve support members and each of the anchor members are angularly spaced from one another around the principal axis; and
a set of prosthetic valve leaflets coupled to the valve support members.
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0 Petitions
Accused Products
Abstract
A cardiac-valve prosthesis which can be used, for example, as a valve for percutaneous implantation. The prosthesis includes an armature for anchorage of the valve prosthesis in the implantation site. The armature defines a lumen for passage of the blood flow and supports a set of prosthetic valve leaflets, which, under the action of the blood flow, are able to move into a radially divaricated condition to enable the flow of the blood through the lumen in a first direction and a radially contracted condition, in which the valve leaflets co-operate with one another and block the flow of the blood through the prosthesis in the opposite direction. The armature includes, in one embodiment, two annular elements connected by anchor members having the capacity of projecting radially with respect to the prosthesis, and support members for the set of leaflets, the support members being carried by at least one of the annular elements so as to leave substantially disengaged the aforesaid lumen for passage of the blood.
411 Citations
19 Claims
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1. A cardiac valve prosthesis adapted for implantation at an implantation site of a patient, the implantation site having an annulus, a plurality of Valsalva sinuses, coronary ostia, and a vessel wall distal to the Valsalva sinuses, the prosthesis having a principal axis extending longitudinally therethrough and comprising:
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an armature adapted for delivery in a radially collapsed configuration and deployment in a radially expanded configuration, the armature defining a lumen for passage of blood flow and comprising; first and second annular elements positioned about the principal axis, the first annular element adapted to engage a wall of the annulus proximal to the Valsalva sinus and the second annular element adapted to engage the vessel wall distal to the Valsalva sinus; a plurality of anchor members extending from the first annular element to the second annular element, each anchor member arching radially outward with respect to the annular elements such that the anchor member is adapted to extend into and generally conform to a respective one of the Valsalva sinuses between the first and second annular elements to enable anchorage of the prosthesis at the implantation site when the cardiac valve prosthesis is deployed at the implantation site with the armature in the radially expanded configuration; and a plurality of valve support members connected to and extending between the first and second annular elements and oriented generally parallel to the principal axis of the prosthesis, wherein each of the valve support members and each of the anchor members are angularly spaced from one another around the principal axis; and a set of prosthetic valve leaflets coupled to the valve support members. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A cardiac valve prosthesis for implantation at an implantation site of a patient, the prosthesis having a principal axis extending longitudinally therethrough and comprising:
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an anchoring structure having a collapsed configuration and an expanded configuration, the anchoring structure defining a lumen; a valve coupled to the anchoring structure and configured such that in the expanded configuration, the valve permits blood flow through the lumen in a first direction and substantially prevents blood flow through the lumen in a second direction opposite the first direction, wherein the anchoring structure includes a first generally cylindrical portion positioned about the principal axis adapted to engage an annular wall of the implantation site proximal to a Valsalva sinus, a second generally cylindrical portion positioned about the principal axis adapted to engage a vessel wall distal to the Valsalva sinus, Valsalva sinus anchoring means for anchoring the prosthesis at the implantation site, the Valsalva sinus anchoring means connected to and extending between the first and second generally cylindrical portions and arching radially outwardly with respect to the first and second generally cylindrical portions for generally conforming to and engaging a wall of the Valsalva sinus of the implantation site between the first generally cylindrical portion and the second generally cylindrical portion, and a plurality of valve support members connected to and extending between the first and second generally cylindrical portions in a direction generally parallel to the principal axis of the prosthesis, wherein each of the valve support members and the Valsalva sinus anchoring means are angularly spaced from one another about the principal axis of the prosthesis. - View Dependent Claims (15, 16, 17, 18)
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19. A method for percutaneous implantation of a cardiac valve prosthesis at an implantation site having an annulus and a Valsalva sinus having a wall and a coronary ostia, the prosthesis having a principal axis extending longitudinally therethrough, the method comprising deploying the prosthesis from a delivery catheter such that a first generally cylindrical portion of the prosthesis positioned about the principal axis engages a wall of the annulus, a second generally cylindrical second portion of the prosthesis positioned about the principal axis engages a vessel wall distal to the Valsalva sinus, a Valsalva sinus anchor portion of the prosthesis expands to a size and shape arching radially outwardly and conforming to the wall of the Valsalva sinus between the first and second generally cylindrical portions, and a plurality of valve leaflet support members extend between the first and second generally cylindrical portions in a direction generally parallel to the principal axis of the prosthesis, wherein each of the valve leaflet support members and the Valsalva sinus anchor portion are angularly spaced from one another about the principal axis of the prosthesis.
Specification