System including machine interface for pumping cassette-based therapies

• US 7,867,189 B2
• Filed: 12/28/2006
• Issued: 01/11/2011
• Est. Priority Date: 07/19/2002
• Status: Expired due to Fees

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Howard, David, Childers, Robert W., Grippo, Paul, Hopping, Andrew D., Yang, Tahua, Bowman, Joseph H. Jr., Vescovi, David, Avoy, Richard, Yu, Alex, Kellam, Benjamin, Booras, John, Jerrell, Jeffrey W., Lauman, Brian, Shang, Sherwin
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Bosworth; Kami A
• Application Number:
  US11/617,527
• Publication Number:
  US 20070213653A1
• Time in Patent Office: 1,475 Days
• Field of Search: 604/5.01, 604/6.11, 604/29, 604/131, 604/31, 604/151, 604/152, 417/477.2, 210/252, 210/258, 210/646
• US Class Current: 604/29
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1562 Details of incorporated reservoirs
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 2205/122 using evacuated interfaces to enhance contact

Abstract

A dialysis machine includes: a hardware unit including at least one pump actuator, at least one valve actuator and a cassette interface, the cassette interface including: (i) a plate that abuts the cassette; (ii) at least one pump aperture defined by the plate; (iii) at least one pump head moveable out of and retractable into the at least one pump aperture to operate a pumping portion of the cassette; (iv) at least one valve aperture defined by the plate; (v) at least one valve apparatus moveable out of and retractable into the at least one valve aperture to operate a valve portion of the cassette; (vi) at least one sensor aperture defined by the plate; and (vii) at least one sensor located in the least one sensor aperture, the at least one sensor operable with a sensor portion of the cassette.

Claims

1. A peritoneal dialysis machine comprising:

a hardware unit including at least one pump actuator having a motor, a rotational to translational converting apparatus coupled to the motor and a pump head coupled to the converting apparatus, at least one valve actuator and a disposable cassette interface forming a wall of the hardware unit for interfacing with a disposable cassette, the cassette interface including;

a plate having at least a portion that is substantially flat and that faces an at least substantially flat flexible sheet of the cassette when loaded into the machine;

at least one pump aperture defined by the at least portion of the plate that is substantially flat;

the at least one pump head translated via the rotational to translational conversion by the motor and the converting apparatus to be moveable out of and retractable into the at least one pump aperture to operate a corresponding pumping portion of the flexible sheet of the cassette, the pump head defining an aperture that enables a vacuum to be pulled through the pump head to the flexible sheet;

at least one valve aperture defined by the at least portion of the plate that is substantially flat;

at least one valve apparatus moveable out of and retractable into the at least one valve aperture to operate a valve portion of the flexible sheet of the cassette;

at least one sensor aperture defined by the at least portion of the plate that is substantially flat; and

at least one sensor located in the least one sensor aperture, the at least one sensor operable with a sensor portion of the flexible sheet of the cassette.

2. The peritoneal dialysis machine of claim 1, wherein at least one of the pump head and the valve apparatus is operated at least partially using negative pressure.

3. The peritoneal dialysis machine of claim 1, wherein at least one of the pump head and the valve apparatus is at least one of:

(i) retracted using negative pressure; and

(ii) pushed out of the associated aperture mechanically.

4. The peritoneal dialysis machine of claim 1, wherein the pump head and the valve apparatus are spring-loaded for outward movement.

5. The peritoneal dialysis machine of claim 1, wherein the pump head and a pump chamber of the flexible sheet pumping portion of the cassette define a dialysis fluid chamber, the pump head being sized to mate with the pump chamber of the flexible sheet pumping portion of the cassette.

6. The peritoneal dialysis machine of claim 1, wherein the valve apparatus is shaped to occlude a valve seat of the flexible sheet valve portion of the cassette.

7. The peritoneal dialysis machine of claim 1, wherein the interface further includes a door placed in a hinged relationship with respect to the plate.

8. The peritoneal dialysis machine of claim 7, wherein the door includes an inflatable bladder that can apply a holding pressure to the cassette.

9. A peritoneal dialysis machine comprising:

an enclosure;

a plate forming a disposable cassette receiving wall of the enclosure, the plate having a first side facing the disposable cassette when the cassette is loaded into the machine;

at least one pump aperture defined by the plate,

at least one valve aperture defined by the plate, and

at least one sensor aperture defined by the plate; and

a base located within the enclosure and behind a second side of the plate;

at least one pump actuator connected to the base and aligned with the at least one pump aperture defined by the plate, the pump actuator including a motor, a rotational to translational converting apparatus coupled to the motor and a shaft connected to the converting apparatus, the shaft leading to a pump head that at least partially forms a vacuum chamber with a flexible membrane of the disposable cassette, the shaft extendable moveably through a seal, the seal enabling a negative pressure to mate the flexible membrane to the pump head;

at least one valve actuator connected to the base and aligned with the at least one valve aperture defined by the plate; and

at least one sensor connected to the base and aligned with the at least one sensor aperture defined by the plate, wherein at least one of the pump actuator, valve actuator and sensor is carried by and removable with the base away from the plate.

10. The peritoneal dialysis machine of claim 9, wherein at least one of:

(i) the plate is connected to the base;

(ii) the at least one pump actuator includes the pump head moveable out of and retractable into the at least one pump aperture to operate a pumping portion of the cassette; and

(iii) the at least one valve actuator includes an apparatus moveable out of and retractable into the at least one valve aperture to operate a valve portion of the cassette.

11. The peritoneal dialysis machine of claim 9, which includes a plurality of pump actuators configured to operate with the cassette so that one pump actuator draws fluid into the cassette as the second pump actuator pushes fluid out of the cassette.

12. The peritoneal dialysis machine of claim 9, wherein the valve actuator is configured to operate using negative pressure.

13. The peritoneal dialysis machine of claim 9, wherein the base includes at least one pneumatic passageway leading to at least one of the pump actuator and the valve actuator.

14. The peritoneal dialysis machine of claim 9, wherein the pump head and a pump chamber of a flexible sheet pumping portion of the cassette define a dialysis fluid chamber.

15. A peritoneal dialysis machine operable with a disposable cassette having a flexible sheet, the machine comprising:

a housing configured to accept a disposable cassette;

a base located inside the housing, the base mounting at least one pump actuator, at least one valve actuator and at least one sensor, the pump actuator including a motor, a rotational to translational converting apparatus, a shaft connected to the converting apparatus and a pump head, the shaft extendable moveably through a seal, the pump head at least partially defining a vacuum chamber with a flexible sheet of the disposable cassette;

a door hinged to the housing and rotatable with respect to the base, the door including an inflatable bladder, the inflatable bladder configured to completely surround a volume of gas for inflation under pressure to thereby press the disposable cassette in operable relationship with the at least one pump actuator, at least one valve actuator and at least one sensor, such that the pump actuator and valve actuator can be selectively moved and pressed against a flexible sheet of the disposable cassette, and such that a negative pressure mates the flexible sheet to the pump head.

16. The peritoneal dialysis machine of claim 15, wherein the housing includes a plate aligned with the base, the operable relationship including the flexible sheet being pressed against the plate, the plate defining at least one pump aperture, at least one valve aperture and at least one sensor aperture.

17. The peritoneal dialysis machine of claim 16, wherein the at least one pump aperture is aligned with the at least one pump actuator, the at least one valve aperture is aligned with the at least one valve actuator and the at least one sensor aperture is aligned with the at least one sensor.

18. The peritoneal dialysis machine of claim 15, wherein the door resides in a horizontal relationship with respect to the base when the machine is set for operation.

19. The peritoneal dialysis machine of claim 15, which is configured such that the inflatable bladder contacts the cassette directly.

20. The peritoneal dialysis machine of claim 15, wherein the pump head and a pump chamber of a flexible sheet pumping portion of the cassette define a dialysis fluid chamber.