Valve with delayed leaflet deployment

• US 7,892,276 B2
• Filed: 12/21/2007
• Issued: 02/22/2011
• Est. Priority Date: 12/21/2007
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Walker, Joseph C., Stocker, Patrick J.
• Primary Examiner(s): McDermott; Corrine M
• Assistant Examiner(s): SHIPMON, TIFFANY P
• Application Number:
  US12/004,561
• Publication Number:
  US 20090164029A1
• Time in Patent Office: 1,159 Days
• Field of Search: 623/1.24, 623/1.26, 623 211- 219, 623/23.68
• US Class Current: 623/1.24
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2433 using balloon catheter
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2250/0059 temporary

Abstract

A valve for use in a body lumen, where the valve includes a valve leaflet with delayed leaflet deployment relative an in vivo implant time. The valve includes a valve frame, a valve leaflet coupled to the valve frame. The valve leaflet includes a commissure that can reversibly seal for unidirectional flow of a liquid through the valve, and a biodegradable adhesive between the valve leaflet and the valve frame to hold at least the commissure of the valve leaflet in a static relationship relative the valve frame for a predetermined time once implanted in vivo.

Claims

1. A valve, comprising:

a valve frame;

a valve leaflet coupled to the valve frame, where the valve leaflet includes a commissure at a distal end of the valve leaflet that can reversibly seal for unidirectional flow of a liquid through the valve; and

a biodegradable adhesive between an outer surface of the distal end of the valve leaflet and the valve frame that holds at least the commissure of the valve leaflet in an open position for a predetermined time of no less than one week after implantation into a lumen of a body;

wherein the valve leaflet in the open position is in a static relationship relative the valve frame for the predetermined amount of time.

2. The valve of claim 1, further including the biodegradable adhesive at one or more discrete attachment points between the valve leaflet and the valve frame that holds the valve leaflet in the static relationship relative the valve frame.

3. The valve of claim 1, where the valve frame includes a distal end and where the biodegradable adhesive holds the valve leaflet completely along the distal end of the valve frame.

4. The valve of claim 1, where the biodegradable adhesive holds at least the commissure of the valve leaflet in the static relationship relative the valve frame for a predetermined time after implantation into a lumen of a body.

5. The valve of claim 1, further including allowing at least a portion of the commissure of the valve leaflet to gather toward the longitudinal axis when the valve frame is in a radially compressed state.

6. The valve of claim 1, where the valve leaflet includes an anti-thrombogenic coating.

7. The valve of claim 1, where the biodegradable adhesive holds at least a portion of the valve leaflet static relative the valve frame once in vivo for a predetermined time of no less than one week.

8. A valve, comprising:

a valve frame;

a valve leaflet coupled to the valve frame, where the valve leaflet includes a commissure at a distal end of the valve leaflet that can reversibly seal for unidirectional flow of a liquid through the valve and an anti-thrombogenie coating; and

a biodegradable adhesive between an outer surface of the distal end of the valve leaflet and the valve frame that holds at least the commissure of the valve leaflet in an open position for a predetermined time of no less than one week after implantation into a lumen of a body;

wherein the valve leaflet in the open position is in a static relationship relative the valve frame for the predetermined time.

9. A system, comprising:

an elongate delivery catheter; and

a valve positioned at least partially over the elongate delivery catheter, where the valve includes;

a valve frame having frame members defining a lumen;

a valve leaflet attached to a portion of the valve frame, the valve leaflet having a commissure at a distal end of the valve leaflet; and

a biodegradable adhesive between an outer surface of the distal end of the valve leaflet and the valve frame that holds at least the commissure of the valve leaflet in an open position for a predetermined time of no less than one week after implantation into a lumen of a body;

wherein the valve leaflet in the open position is in a static relationship relative the valve frame for the predetermined amount of time.

10. The system of claim 9, where the elongate delivery catheter includes an expandable balloon positioned around at least a portion of the elongate delivery catheter, and where the valve is positioned at least partially over the expandable balloon.

11. The system of claim 9, where the elongate delivery catheter includes a retractable sheath positioned over at least a portion of the valve, where the retractable sheath can be retracted to release the valve from the elongate delivery catheter.

12. The system of claim 9, further including the biodegradable adhesive at one or more discrete attachment points between the valve leaflet and the valve frame that holds the valve leaflet in the static relationship relative the valve frame.

13. The system of claim 9, where the valve frame includes the distal end and where the biodegradable adhesive holds the valve leaflet completely along the distal end of the valve frame.