Method and apparatus for measuring sample reaction results on biosensor

• US 7,897,033 B2
• Filed: 07/05/2006
• Issued: 03/01/2011
• Est. Priority Date: 08/08/2005
• Status: Active Grant

• Current Assignee: Osang Healthcare Co., Ltd.
• Original Assignee: INFOPIA CO., LTD
• Inventors: Yoo, Jin-a, Lee, Sung-dong, Suk, Hong-seong, Bae, Byeong-woo
• Primary Examiner(s): Neckel; Alexa D
• Assistant Examiner(s): Dieterle; Jennifer
• Application Number:
  US11/481,086
• Publication Number:
  US 20100243481A1
• Time in Patent Office: 1,700 Days
• Field of Search: 204/403.01, 204/403.02, 204/403.03, 204/403.04, 204/403.05, 204/403.06, 204/403.07, 204/403.08, 204/403.09, 204/403.1, 204/403.11, 204/403.12, 204/403.13, 204/403.14, 204/403.15, 205/777.5, 205/778, 205/792, 600345-349, 422 681- 98, 435 4- 40, 436 62- 71, 436500-548
• US Class Current: 205/792
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.

Claims

1. A method of measuring sample reaction results on a biosensor having a checking electrode, a working electrode and a counter electrode, comprising:

applying voltage between the checking and working electrodes;

injecting sample into a sample receiving region;

measuring first current between checking and working electrodes;

applying voltage between the working and counter electrodes;

measuring second current between the working and counter electrodes;

measuring a time interval from a time at which the first current begins to be detected to a time at which the second current begins to be detected;

comparing the first and second currents with a predetermined threshold current value and the time interval with a predetermined time value;

if the first and second currents are greater than the predetermined threshold current value and the time interval is less than the predetermined time value, re-applying voltage between the working and counter electrodes, and then measuring third current between the working and counter electrodes; and

computing a concentration value corresponding to the third current as the sample reaction results.

2. The method of claim 1, wherein the concentration value is acquired from a concentration value table stored in a memory.

3. The method of claim 1, wherein the concentration value is acquired by operating a predetermined factor to the amount of the third current.

4. A method of measuring sample reaction results on a biosensor having at least a working electrode, a checking electrode, and a counter electrode, comprising:

applying voltage between the checking electrode and the working electrode, and between the counter electrode and the working electrode, and detecting the amount of currents flowing through the working electrode, and a time interval between times when the amount of two currents is detected;

determining whether or not a sample is properly injected by comparing the amount of detected currents and the detected time interval with predetermined threshold values;

if it is determined that the sample is properly injected, applying voltage between the working electrode and the counter electrode and re-detecting the amount of current flowing through the working electrode; and

acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of re-detected current.

5. The method of claim 4, wherein the concentration value is acquired from a concentration value table stored in a memory.

6. The method of claim 4, wherein the concentration value is acquired by operating a predetermined factor to the amount of re-detected current.