Regimens for intra-articular viscosupplementation

  • US 7,931,030 B2
  • Filed: 12/20/2005
  • Issued: 04/26/2011
  • Est. Priority Date: 12/30/2004
  • Status: Expired due to Fees
First Claim
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1. A method for treating a knee joint of a subject suffering from osteoarthritis in said joint, the method comprising a treatment regimen, the regimen being characterized by the step of administering a single administration dose, within a 24 hour period, of a viscosupplement intra-articularly into the knee joint of said subject,wherein said viscosupplement administered in the single administration dose:

  • is a hyaluronan (HA) based viscosupplement that does not contain additional active components, andcomprises between 24 mg to 100 mg of HA, andcomprises a crosslinked HA, andhas a residence half-life in said knee joint of between 0.2 days to 8.8 days;

    wherein said treatment regimen does not comprise administering the viscosupplement in weekly intervals.

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