Intravascularly implantable integrated circuits

• US 7,935,056 B2
• Filed: 03/29/2007
• Issued: 05/03/2011
• Est. Priority Date: 09/02/2004
• Status: Active Grant

• Current Assignee: Proteus Digital Health, Inc. (Otsuka Holdings Company Limited)
• Original Assignee: Proteus Biomedical, Inc. (Otsuka Holdings Company Limited)
• Inventors: Zdeblick, Mark J.
• Primary Examiner(s): Bertram; Eric D.
• Application Number:
  US11/731,247
• Publication Number:
  US 20070185537A1
• Time in Patent Office: 1,496 Days
• Field of Search: 607/9, 607/115, 607/2, 600/300
• US Class Current: 600/300
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/341 Vectorcardiography [VCG]
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3684 for stimulating the heart at multiple sites of the ventricle or the atrium
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation
• CPC Class Codes: A61N 1/3686 configured for selecting the electrode configuration on a lead A61N1/3688 takes precedence
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators
• CPC Class Codes: A61N 1/37211 Means for communicating with stimulators
• CPC Class Codes: A61N 1/37276 characterised by means for reducing power consumption during telemetry
• CPC Class Codes: A61N 1/37288 Communication to several implantable medical devices within one patient
• CPC Class Codes: A61N 2001/0585 Coronary sinus electrodes

Abstract

Techniques for controlling one or more modular circuits (“satellites”) that are intended for placement in a subject'"'"'s body. The one or more satellites are controlled by sending signals over a bus that includes first and second conduction paths. Also coupled to the bus in system embodiments is a device such as a pacemaker that provides power and includes control circuitry. Each satellite includes satellite circuitry and one or more effectors that interact with the tissue. The satellite circuitry is coupled to the bus, and thus interfaces the controller to the one or more effectors, which may function as actuators, sensors, or both. The effectors may be electrodes that are used to introduce analog electrical signals (e.g., one or more pacing pulses) into the tissue in the local areas where the electrodes are positioned (e.g., heart muscles) or to sense analog signals (e.g., a propagating depolarization signal) within the tissue.

Claims

1. An implantable integrated circuit to control an electrode, the implantable integrated circuit comprising:

a power recovery circuit configured to supply power;

a data/clock recovery circuit configured to derive and recover digital data signal to control the electrode, wherein the data/clock recovery circuit is further configured to implement a sleep state of the data/clock recovery circuit in response to a receipt of a sleep signal;

a command interpretation circuit configured to receive the digital data signal from the data/clock recovery circuit and to map the digital data signals into control commands; and

an electrode control circuit configured to receive the control commands from the command interpretation circuit and to identify and control the electrode based on the control commands.

2. The implantable integrated circuit according to claim 1, wherein the power recovery circuit comprises a capacitor.

3. The implantable integrated circuit according to claim 1, further comprising an initialization generation circuit configured to generate initialization signals when the digital data signals exceed predetermined voltage thresholds.

4. The implantable integrated circuit according to claim 1, wherein the electrode control circuit comprises electrode registers.

5. The implantable integrated circuit according to claim 1, wherein the electrode control circuit comprises electrode drivers and switches.

6. The implantable integrated circuit according to claim 1, wherein the power recovery circuit is refreshed by drawing a current of a few picoamps.

7. The implantable integrated circuit according to claim 1, further comprising a bus.

8. The implantable integrated circuit according to claim 7, wherein the bus is a two-wire bus.

9. The implantable integrated circuit according to claim 7, wherein the electrode control circuit is coupled to one or more electrodes in addition to the electrode.

10. The implantable integrated circuit according to claim 1, wherein the data/clock recovery circuit is coupled to a central controller of the electrode.

11. The implantable integrated circuit according to claim 10, wherein the central controller comprises a pacemaker.

12. The implantable integrated circuit according to claim 10, wherein the central controller comprises a switching circuit.