System and method for determining drug administration information

• US 7,941,200 B2
• Filed: 12/08/2005
• Issued: 05/10/2011
• Est. Priority Date: 12/08/2005
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Galley, Paul, Wagner, Robin, Chittajallu, Siva, Thukral, Ajay, Weinert, Stefhan, Long, James R., Buck, Harvey, Marco, Kym, Bousamra, Steven
• Primary Examiner(s): Marmor, II; Charles A
• Assistant Examiner(s): D'ANGELO, MICHAEL J
• Application Number:
  US11/297,733
• Publication Number:
  US 20070179434A1
• Time in Patent Office: 1,979 Days
• Field of Search: 600/365, 600345-347, 604 65- 67, 702/19
• US Class Current: 600/347
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics
• CPC Class Codes: G06F 9/451 Execution arrangements for user interfaces
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/60 relating to nutrition control, e.g. diets
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

A system for determining drug administration information may comprise an input device providing for user input of feed forward information having a first parameter component and a second parameter component, a data storage device and a processor. The data storage device may have stored therein a map correlating values of the first and second parameters to drug administration information. The processor may be responsive to user input of the feed forward information to determine corresponding drug administration information according to the map.

Claims

1. A system for determining drug administration information for a user based at least on the user ingesting a meal, the system comprising:

an input device providing for user input of feed forward information in the form of meal information having a first parameter component corresponding to carbohydrate content of the meal and a second parameter component corresponding to an expected speed of overall glucose absorption from the meal by the user, wherein the meal information relates to a meal that is to be ingested in the future,

a data storage device having stored therein a map correlating values of the first and second parameter components to drug administration information, and

a processor responsive to the user input of the feed forward information to determine corresponding drug administration information according to the map,

wherein the input device includes a display unit, and wherein the processor controls the display unit to display a graphical user interface,

wherein the graphical user interface has a first axis defined by values of the first parameter component and a second axis defined by values of the second parameter component, the graphical user interface providing for the user input of feed forward information in the form of a user selection of a corresponding pair of values of the first and second parameter components; and

wherein the input device and the processor provide the user with the ability to modify one or more of time and date stamp information that is associated with previously entered meal information subsequent to actual meal ingestion.

2. The system according to claim 1 wherein the graphical user interface includes a touch responsive interface and defines a grid-type user interface providing for the user selection of a corresponding pair of values of the first and second parameter components.

3. The system according to claim 1 wherein the graphical user interface defines a continuous function of the first and second parameter components.

4. The system according to claim 1 wherein the drug administration information relates to a blood glucose lowering drug or insulin.

5. The system according to claim 1 wherein the processor controls the display unit to display via the graphical user interface values of the carbohydrate content in a format selected from direct estimates of carbohydrate weight, meal size values, and meal size values relative to a reference meal size.

6. The system according to claim 1 wherein the processor controls the display unit to display via the graphical user interface values of the expected speed in a format selected from meal duration values, meal duration values relative to a reference meal duration, and total glycemic index values.

7. The system according to claim 1 wherein the processor controls the display unit to display via the graphical user interface values of the expected speed in a format comprising a fat amount, a protein amount, and a carbohydrate amount, and displays the values of the carbohydrate content in a format comprising meal size values for each of the fat amount, protein amount and carbohydrate amount.

8. The system according to claim 1 wherein the graphical user interface provides for the user input of feed forward information in a format comprising a user selection of a meal size value in terms of fat amount, a meal size in terms of protein amount, and a meal size in terms of carbohydrate amount and wherein the processor controls the display unit to display via the graphical user interface the meal size values in the form of fat amount, protein amount and carbohydrate amount relative to reference meal size values in terms of fat, protein and carbohydrate amounts respectively.

9. The system according to claim 1 wherein the input device provides for user input of additional feed forward information comprising at least one of exercise information, user stress information, user illness information, and user menstrual cycle information,

wherein the data storage device has stored therein an additional map correlating the at least one of the exercise information, the user stress information, the user illness information, and the user menstrual cycle information to modification information, and

wherein the processor is responsive to user input of the at least one of the exercise information, the user stress information, the user illness information, and the user menstrual cycle information to modify the corresponding drug administration information according to the modification information determined via the additional map.

10. The system according to claim 1 wherein the processor is operable to determine whether a complete user input to the graphical user interface has been detected, and wherein the processor is operable to time and date stamp the graphical user interface input and to enter the date and time stamped graphical user interface input into a database contained within the data storage device if the processor detects that a complete user input to the graphical user interface has occurred.

11. The system according to claim 1 wherein the system provides the user with the ability to append new or more accurate information onto the previously entered meal information.

12. The system according to claim 1 wherein the processor controls the display unit to display via the graphical user interface at least some of the corresponding drug administration information.

13. The system according to claim 12 wherein the processor monitors occurrences of user acceptance and rejection of the displayed corresponding drug administration information determined according to the map, and determines whether the system is acceptable for use by the user based at least in part on the occurrences of user acceptance and rejection of the corresponding drug administration information.

14. The system of claim 13 wherein, if the processor determines that the system is acceptable for use by the user, then the processor determines whether the system requires recalibration based at least in part on the occurrences of user acceptance and rejection of the drug administration information.

15. The system of claim 1 further comprising means for providing for input of user feedback information, and wherein the processor monitors the user feedback information and determines whether the system is acceptable for use by the user based at least in part on the user feedback information.

16. The system of claim 15 wherein, if the processor determines that the system is acceptable for use by the user, then the processor determines whether the system requires recalibration based at least in part on the user feedback information.

17. The system of claim 1 further comprising means for providing for input of health care professional feedback information, and wherein the processor monitors the health care professional feedback information and determines whether the system is acceptable for use by the user based at least in part on the health care professional feedback information.

18. The system of claim 17 wherein, if the processor determines that the system is acceptable for use by the user, then the processor determines whether the system requires recalibration based at least in part on the health care professional feedback information.

19. The system of claim 1 further comprising at least one model-based function responsive to measurement of one or more user conditions to estimate another user condition different than the one or more user conditions, and wherein the processor monitors the at least one model-based function and determines whether the system is acceptable for use by the user based at least in part on the at least one model-based function.

20. The system of claim 19 wherein, if the processor determines that the system is acceptable for use by the user, then the processor determines whether the system requires recalibration based at least in part on the at least one model-based function.