Implantable infusion device with multiple controllable fluid outlets

• US 8,002,747 B2
• Filed: 05/26/2006
• Issued: 08/23/2011
• Est. Priority Date: 05/26/2005
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Alfred E. Mann Foundation For Scientific Research
• Inventors: Das, Stephen D., Lord, Peter C., Gibson, Scott R.
• Primary Examiner(s): Stigell; Theodore J
• Assistant Examiner(s): GRAY, PHILLIP A
• Application Number:
  US11/420,641
• Publication Number:
  US 20060270983A1
• Time in Patent Office: 1,915 Days
• Field of Search: 604/131, 6048901-8921, 604118-121, 60428801-28804
• US Class Current: 604/131
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407

Abstract

An implantable infusion system includes at least two controllable fluid transfer devices that may be used to transfer different fluid flows to the same or different body sites.

Claims

1. An infusion device configured for implantation in a patient'"'"'s body, the infusion device comprising:

a housing;

a reservoir mounted in the housing and configured to contain at least one fluid medication;

a first fluid transfer device mounted in the housing actuatable to transfer a first fluid flow from a first fluid inlet coupled to the reservoir to a first fluid outlet;

a second fluid transfer device mounted in the housing actuatable to transfer a second fluid flow from a second fluid inlet coupled to the reservoir to a second fluid outlet;

a common electrically powered actuator, including a rod formed from magnetic material that is driven in a first direction in a first actuation mode and is driven in a second direction that is different than the first direction in a second actuation mode, positioned relative to the first and second fluid transfer devices such that the rod formed from magnetic material actuates the first fluid transfer device when in the first actuation mode, actuates the second fluid transfer device when in the second actuation mode, and does not actuate the first and second fluid transfer devices when in a neutral mode; and

a controller mounted in the housing that controls the common actuator.

2. The infusion device of claim 1 wherein the first fluid transfer device comprises a first pump mechanism.

3. The infusion device of claim 1 wherein the first fluid transfer device comprises a valve mechanism.

4. The infusion device of claim 1 wherein the first fluid transfer device includes a first fluid chamber and a first pump element mounted for movement between an intake position and a discharge position;

and

the common actuator is configured to move the first pump element to the discharge position when in the first actuation mode.

8. The infusion device of claim 1 wherein the housing defines at least one fill port coupled to the reservoir.

9. The infusion device of claim 1 wherein the controller includes electronic circuitry for specifying a first fluid flow delivery schedule and for controlling the common actuator in accordance with the schedule.

10. The infusion device of claim 1 wherein the controller is adapted to operates the common actuator to actuate the first fluid transfer device at a constant rate and actuate the second fluid transfer device a variable rate.

11. The infusion device of claim 1 wherein the controller includes electronic circuitry for specifying first and second fluid flow delivery schedules and for controlling the common actuator in accordance with the first and second schedules.

12. The infusion device of claim 1 wherein

the reservoir includes at least first and second reservoir compartments;

the first fluid inlet is coupled to the first reservoir compartment; and

the second fluid inlet is coupled to the second reservoir compartment.

13. The infusion device of claim 12 wherein the first fluid transfer device comprises a pump mechanism.

14. The infusion device of claim 12 wherein the first fluid transfer device includes a valve mechanism.

15. The infusion device of claim 12 wherein

the first fluid transfer device comprises a first fluid chamber and a first piston mounted for reciprocal linear movement between an intake position and a discharge position;

and

the second fluid transfer device comprises a second fluid chamber and a second piston mounted for reciprocal linear movement between an intake position and a discharge position.

16. The infusion device of claim 15, wherein the armature moves the first piston to its discharge position during the first actuation mode and moves the second piston to its discharge position during the second actuation mode.

17. The infusion device of claim 12 wherein the reservoir includes a pressure transmissive interior partition between the first and second reservoir compartments configured to equalize pressure within the first and second reservoir compartments.

18. The infusion device of claim 17 further comprising

means for producing a reference pressure internal to the reservoir compartments.

19. The infusion device of claim 18 wherein the reference pressure is negative with respect to ambient pressure.

20. The infusion device of claim 12 wherein the housing includes first and second fill ports respectively coupled to the first and second reservoir compartments.

21. The infusion device of claim 12 wherein the housing includes first and second outlet ports adapted to be coupled to first and second catheters.

22. The infusion device of claim 12 wherein the housing includes first and second outlet ports adapted to be coupled to catheter means for delivering the first fluid flow to a first body site and the second fluid flow to a second body site different from the first body site.

25. The infusion device of claim 1 further comprising

a biasing apparatus configured to drive the rod formed from magnetic material to a neutral position at the end of the first actuation mode and to drive the rod formed from magnetic material the neutral position at the end of the second actuation mode.

26. The infusion device of claim 25 wherein

the rod formed from magnetic material defines first and second longitudinal ends;

and

the biasing apparatus includes a first resilient device associated with the first longitudinal end of the rod formed from magnetic material and a second resilient device associate with the second longitudinal end of the rod formed from magnetic material.

5. An infusion device configured for implantation in a patient'"'"'s body, the infusion device comprising:

a housing;

a reservoir mounted in the housing and configured to contain at least one fluid medication;

a first fluid transfer device in the housing including a first fluid chamber and a first piston mounted for reciprocal linear movement between an intake position and a discharge position and actuatable to transfer a first fluid flow from a first fluid inlet coupled to the reservoir to a first fluid outlet;

a second fluid transfer device in the housing including a second fluid chamber and a second piston mounted for reciprocal linear movement between an intake position and a discharge position and actuatable to transfer a second fluid flow from a second fluid inlet coupled to the reservoir to a second fluid outlet;

a common actuator including a single movable actuation structure that moves in a first direction and strikes the first piston with sufficient force to move the first piston to its discharge position when in a first actuation mode, moves in a second direction that is different than the first direction and strikes the second piston with sufficient force to move the second piston to its discharge position when in a second actuation mode, and does not strike the first and second pistons when in a neutral mode; and

a controller mounted in the housing that controls the common actuator.

6. The infusion device of claim 5 wherein the single movable actuation structure comprises a linearly movable member that is configured to move in a first direction during the first actuation mode and is configured to move in a second direction during the second actuation mode.

7. The infusion device of claim 5 wherein the single movable actuation structure comprises an armature that is driven in a first direction during the first actuation mode and is driven in a second direction during the second actuation mode.

23. The infusion device of claim 5 wherein the common actuator comprises an electrically powered actuator and the single movable actuation structure comprises an armature that is driven in a first direction during the first actuation mode and is driven in a second direction during the second actuation mode.

24. The infusion device of claim 5 wherein the single movable actuation structure comprises a piezo element that is configured to deflect in a first direction during the first actuation mode and is configured to deflect in a second direction during the second actuation mode.

27. The infusion device of claim 5 further comprising

a biasing apparatus configured to drive the single movable actuation structure to a neutral position, where the single movable actuation structure is not in contact with the first and second pistons, at the end of the first actuation mode and to drive the common actuator the neutral position at the end of the second actuation mode.

28. The infusion device of claim 27 wherein

the single movable actuation structure defines first and second longitudinal ends;

and

the biasing apparatus includes a first resilient device associated with the first longitudinal end of the single movable actuation structure and a second resilient device associate with the second longitudinal end of the single movable actuation structure.

29. The infusion device of claim 5 wherein the controller is adapted to operates the common actuator to actuate the first fluid transfer device at a constant rate and actuate the second fluid transfer device a variable rate.

30. The infusion device of claim 5 wherein the controller includes electronic circuitry for specifying first and second fluid flow delivery schedules and for controlling the common actuator in accordance with the first and second schedules.

31. The infusion device of claim 5 wherein

the reservoir includes at least first and second reservoir compartments;

the first fluid inlet is coupled to the first reservoir compartment; and

the second fluid inlet is coupled to the second reservoir compartment.