Signal analysis in implantable cardiac treatment devices

• US 8,014,851 B2
• Filed: 09/26/2006
• Issued: 09/06/2011
• Est. Priority Date: 09/26/2006
• Status: Active Grant

• Current Assignee: Cameron Incorporated (Schlumberger NV)
• Original Assignee: Cameron Incorporated (Schlumberger NV)
• Inventors: Ostroff, Alan H., Allavatam, Venugopal, Phillips, James W.
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Sarcione; Jessica
• Application Number:
  US11/527,184
• Publication Number:
  US 20080077030A1
• Time in Patent Office: 1,806 Days
• Field of Search: 600515-518, 600/521
• US Class Current: 600/515
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61B 5/366 Detecting abnormal QRS complex, e.g. widening
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0563 specially adapted for defibrillation or cardioversion
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting

Abstract

Methods and devices for cardiac signal analysis in implantable cardiac therapy systems. Several signal processing and/or conditioning methods are shown including R-wave detection embodiments including the use of thresholds related to previous peak amplitudes. Also, some embodiments include sample thresholding to remove extraneous data from sampled signals. Some embodiments include weighting certain samples more heavily than other samples within a sampled cardiac signal for analysis.

Claims

1. A method of determining whether a patient is undergoing a malignant cardiac condition in an implantable cardiac stimulus device (ICSD) comprising a canister coupled to a plurality of electrodes, the method comprising:

the ICSD capturing a cardiac signal having a cardiac event from a patient using implanted the plurality of electrodes;

the ICSD detecting a cardiac event in the cardiac signal by comparing the cardiac signal to a detection threshold;

the ICSD sampling and windowing the cardiac signal such that it is comprised of a plurality of signal samples representing a time varying amplitude of the captured cardiac signal during a window of time corresponding to the detected cardiac event; and

the ICSD comparing the sampled and windowed cardiac signal to a stored template by determining a difference between a sample value for each sample in the sampled and windowed cardiac signal and a corresponding template value for each sample in the stored template to create a series of difference values, multiplying the series of difference values by a weighting vector to create a series of difference products and summing the series of difference products to yield a score indicative of correlation between the cardiac signal and the stored template,

wherein at least some of the signal samples are provided with greater weight and others of the signal samples are provided with a lesser weight by the weighting vector.

2. The method of claim 1, wherein the stored template includes a fiducial point, and the weighting vector is configured such that greater weight is given to samples nearer the fiducial point than other samples.

3. The method of claim 1, wherein the stored template includes one or more slopes, wherein the weighting vector is configured such that lesser weight is given to samples taking taken along a sloped portion of the stored template.

4. An implantable cardiac stimulus device (ICSD) comprising a canister housing operational circuitry and a plurality of electrodes electrically coupled to the operational circuitry, the operational circuitry being configured to perform a method of signal analysis to determine whether a patient is undergoing a malignant cardiac condition comprising:

capturing a cardiac signal from the electrodes;

detecting a cardiac event in the cardiac signal by comparing the cardiac signal to a detection threshold;

sampling and windowing the cardiac signal such that it is comprised of a number of signal samples representing a time varying amplitude of the captured cardiac signal during a window of time corresponding to the detected cardiac event; and

comparing the sampled and windowed cardiac signal to a stored template by determining a difference between a sample value for each sample in the sampled and windowed cardiac signal and a corresponding template value for each sample in the stored template to create a series of difference values, multiplying the series of difference values by a weighting vector to create a series of difference products and summing the series of difference products to yield a score indicative of correlation between the cardiac signal and the stored template,

wherein at least some of the signal samples are provided with greater weight and others of the signal samples are provided with a lesser weight by the weighting vector.

5. The ICSD of claim 4 wherein the operational circuitry is further configured to identify a fiducial point based on the stored template, and the weighting vector gives greater weight to samples nearer the fiducial point than other samples.

6. The ICSD of claim 4 wherein the operational circuitry is further configured such that the weighting vector gives lesser weight to samples taken along a sloped portion of the stored template.