Composition and method for treating skin

• US 8,017,138 B2
• Filed: 12/12/2008
• Issued: 09/13/2011
• Est. Priority Date: 06/23/1999
• Status: Expired due to Fees

• Current Assignee: Dr Dennis Gross Skincare LLC (Dr. Dennis Gross Skincare)
• Original Assignee: Dennis Gross
• Inventors: Gross, Dennis
• Primary Examiner(s): Yu; Gina C
• Application Number:
  US12/334,216
• Publication Number:
  US 20090131375A1
• Time in Patent Office: 1,005 Days
• Field of Search: 424/401, 424/446, 514/159, 514/163, 514/845, 514/847
• US Class Current: 424/401
• CPC Class Codes: A61K 2800/28 Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
• CPC Class Codes: A61K 2800/884 Sequential application
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61K 8/19 containing inorganic ingredients
• CPC Class Codes: A61K 8/365 Hydroxycarboxylic acids; Ketocarboxylic acids
• CPC Class Codes: A61K 8/368 with carboxyl groups directly bound to carbon atoms of aromatic rings
• CPC Class Codes: A61K 8/39 Derivatives containing from 2 to 10 oxyalkylene groups
• CPC Class Codes: A61K 8/86 Polyethers
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations

Abstract

A method for the topical treatment of skin aging and acne and the improvement of skin appearance is disclosed. Compositions for use in this method and a kit containing such compositions are also disclosed. In some of the embodiments of the invention, either one, or both, of the acid composition and neutralizing composition useful in the method for the topical treatment of skin aging and acne and the improvement of skin appearance are of low viscosity. The compositions and methods are effective but gentle enough to be suitable for daily home use by the consumer.

Claims

1. A method for treating skin, comprising the sequential steps of:

a) applying to the skin a first dermatological liquid composition comprising an effective amount of a skin renewal stimulating acid, about 0.1% to about 10% by weight of at least one surfactant/emulsifying agent and a cosmetically acceptable vehicle, wherein the pH of the first dermatological liquid composition is between about 2.5 and about 4; and

thereafter

b) neutralizing the first dermatological liquid composition by applying to the skin a second dermatological liquid composition comprising an alkaline agent suitable for use in a skin care composition, about 0.1% to about 10% by weight of at least one surfactant/emulsifying agent and a cosmetically acceptable vehicle, wherein the pH of the second dermatological liquid composition ranges from greater than about 7 to about 12.

2. The method of claim 1 wherein the pH of the second dermatological liquid composition is between about 7.1 and about 12.

3. The method of claim 2 wherein the pH of the second dermatological liquid composition is between about 8 and about 8.5.

4. The method of claim 1 wherein the amount of the at least one surfactant/emulsifying agent in the second dermatological liquid composition is from about 1% to about 5%.

5. The method of claim 4 wherein the amount of the at least one surfactant/emulsifying agent in the second dermatological liquid composition is from about 2% to about 3%.

6. The method of claim 5 wherein the at least one surfactant/emulsifying agent of the second dermatological liquid composition is selected from the group consisting of ceteareths, ceteths, cetyl alcohol, deceths, dodoxynols, glyceryl palmitate, glyceryl stearate, laneths, myreths, nonoxynols, octoxynols, oleths, PEG-castor oil, poloxamers, poloxamines, polysorbates, ammonium laureth sulfate, sodium laureth sulfate, and mixtures thereof.

7. The method of claim 1 wherein the acid in the first dermatological liquid composition is present from about 1% to about 3%.

8. The method of claim 7 wherein the acid in the first dermatological liquid composition is present in about 2%.

9. The method of claim 1 wherein the first dermatological liquid composition and the second dermatological liquid composition are each applied with use of a pad.

10. The method of claim 1 wherein the first dermatological liquid composition and the second dermatological liquid composition are each applied with use of a cotton ball.

11. The method of claim 1 wherein the first dermatological liquid composition and the second dermatological liquid composition are each applied with use of a cotton-tipped applicator.

12. The method of claim 1 wherein the effective amount of the acid is from about 0.1% to about 5%.

13. The method of claim 1 wherein the acid is a hydrophilic acid.

14. The method of claim 1 wherein the first dermatological liquid composition and the second dermatological liquid composition are applied to a face.

15. The method of claim 1 wherein the first dermatological liquid composition is allowed to dry on the skin for about 3 minutes.

16. The method of claim 1, wherein the acid in the first dermatological liquid composition is selected from the group consisting of hydroxy carboxylic acids, keto acids, hydroxybenzoic acids and mixtures thereof.

17. The method of claim 16, wherein the acid in the first dermatological liquid composition is selected from alpha hydroxy acids and mixtures thereof.

18. The method of claim 16, wherein the acid in the first dermatological liquid composition is selected from the group consisting of glycolic acid, lactic acid, malic acid, tartaric acid, citric acid, ascorbic acid, mandelic acid, azelaic acid, glyceric acid, tartronic acid, gluconic acid, benzylic acid, pyruvic acid, 2-hydroxybutyric acid, salicylic acid, trichloroacetic acid, and mixtures thereof.

19. The method of claim 1, wherein the at least one surfactant/emulsifying agent in the first dermatological liquid composition is selected from octoxynol-9 and polysorbate-20;

and the at least one surfactant/emulsifying agent in the second dermatological liquid composition is selected from octoxynol-9 and polysorbate-20.

20. The method of claim 1, wherein the first dermatological liquid composition comprises about 2% to about 6% by weight of the at least one surfactant/emulsifying agent.

21. The method of claim 1, wherein the first dermatological liquid composition comprises about 3% to about 5% by weight of the at least one surfactant/emulsifying agent.

22. The method of claim 19, wherein the at least one surfactant/emulsifying agent in the first dermatological liquid composition is selected from the group consisting of ceteareths, ceteths, cetyl alcohol, deceths, dodoxynols, glyceryl palmitate, glyceryl stearate, laneths, myreths, nonoxynols, octoxynols, oleths, PEG-castor oil, poloxamers, poloxamines, polysorbates, ammonium laureth sulfate, sodium laureth sulfate, and mixtures thereof.

23. The method of claim 22, wherein the at least one surfactant/emulsifying agent in the first dermatological liquid composition is selected from the group consisting of octoxynol-9 and polysorbate-20.

24. The method of claim 6, wherein the at least one surfactant/emulsifying agent in the second dermatological liquid composition is selected from the group consisting of octoxynol-9 and polysorbate-20.

25. The method of claim 1, wherein the alkaline agent in the second dermatological liquid composition is selected from sodium bicarbonate, sodium carbonate, sodium hydroxide, ammonia, triethanolamine, sodium hydrogen phosphate and sodium dihydrogen phosphate.

26. The method of claim 25, wherein the alkaline agent in the second dermatological liquid composition is sodium bicarbonate or sodium carbonate.

27. The method of claim 25, wherein the alkaline agent in the second dermatological liquid composition is selected from sodium hydroxide, ammonia and triethanolamine.

28. The method of claim 1, wherein the first dermatological composition is applied to the skin by massaging into the skin in step a), and the second dermatological composition is applied to the skin by massaging into the skin in step b).

30. The method of claim 1, wherein the first dermatological liquid composition has a viscosity in the range of about 1 cps to about 300 cps, and the second dermatological liquid composition has a viscosity in the range of about 1 cps to about 300 cps.

31. The method of claim 30, wherein the first dermatological liquid composition has a viscosity in the range of about 1 cps to about 200 cps, and the second dermatological liquid composition has a viscosity in the range of about 1 cps to about 200 cps.

32. The method of claim 31, wherein the first dermatological liquid composition has a viscosity in the range of about 1 cps to about 100 cps, and the second dermatological liquid composition has a viscosity in the range of about 1 cps to about 100 cps.

33. The method of claim 32, wherein the first dermatological liquid composition has a viscosity in the range of about 1 cps to about 20 cps, and the second dermatological liquid composition has a viscosity in the range of about 1 cps to about 20 cps.

34. The method of claim 1, wherein the first dermatological liquid composition has a viscosity in the range of about 10 cps to about 500 cps, and the second dermatological liquid composition has a viscosity in the range of about 10 cps to about 500 cps.

35. The method of claim 34, wherein the first dermatological liquid composition has a viscosity in the range of about 10 cps to about 400 cps, and the second dermatological liquid composition has a viscosity in the range of about 10 cps to about 400 cps.

36. The method of claim 34, wherein the first dermatological liquid composition has a viscosity in the range of about 20 cps to about 500 cps, and the second dermatological liquid composition has a viscosity in the range of about 20 cps to about 500 cps.

29. A method for treating skin, comprising the sequential steps of:

a) applying to the skin a first dermatological liquid composition comprising an effective amount of a skin renewal stimulating acid, at least one surfactant/emulsifying agent and a cosmetically acceptable vehicle, wherein the pH of the first dermatological liquid composition is between about 2.5 and about 4; and

thereafter

b) neutralizing the first dermatological liquid composition by applying to the skin a second dermatological liquid composition comprising an alkaline agent suitable for use in a skin care composition, at least one surfactant/emulsifying agent and a cosmetically acceptable vehicle, wherein the pH of the second dermatological liquid composition ranges from greater than about 7 to about 12,

wherein the first dermatological liquid composition comprises the following ingredients;