Variable volume, shape memory actuated insulin dispensing pump

• US 8,029,245 B2
• Filed: 12/29/2008
• Issued: 10/04/2011
• Est. Priority Date: 10/09/2002
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Reggiardo, Christopher V., Rush, Benjamin M., Anderson, Arthur E. III
• Primary Examiner(s): Kramer; Devon C
• Assistant Examiner(s): KASTURE, DNYANESH G
• Application Number:
  US12/345,586
• Publication Number:
  US 20090105648A1
• Time in Patent Office: 1,009 Days
• Field of Search: 417/44.1, 417/12, 417/199.2, 417/200, 222/52, 222/63, 318/117, 605/27, 605/28
• US Class Current: 417/199.2
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 2205/0288 Electro-rheological or magneto-rheological materials
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/702 automatically during use
• CPC Class Codes: A61M 5/14216 Reciprocating piston type
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: F03G 7/065 using a shape memory element
• CPC Class Codes: F04B 17/00 Pumps characterised by combination with, or adaptation to, specific driving engines or motors
• CPC Class Codes: F04B 2201/0201 Position of the piston
• CPC Class Codes: F04B 23/02 having reservoirs
• CPC Class Codes: F04B 35/00 Piston pumps specially adapted for elastic fluids and characterised by the driving means to their working members, or by combination with, or adaptation to, specific driving engines or motors, not otherwise provided for
• CPC Class Codes: F04B 35/04 the means being electric
• CPC Class Codes: F04B 49/065 and making use of computers
• CPC Class Codes: F04B 9/00 Piston machines or pumps characterised by the driving or driven means to or from their working members
• CPC Class Codes: F04B 9/02 the means being mechanical
• CPC Class Codes: F05C 2251/08 Shape memory
• CPC Class Codes: G01F 11/021 of the piston type G01F11/04 takes precedence

Abstract

A portable pumping system provides insulin or other drugs to a user. A shape memory element is used to actuate the pump and an intelligent system controls the actuator in order to minimize stresses within the system and provide accurate and reliable dosage delivery. The control system utilizes various types of feedback to monitor and optimize the position of the pumping mechanisms. Physical design aspects also minimize stress and the combination of the physical design aspects and the intelligent operation of the system results in a lightweight and cost effective pump that may be used in a disposable fashion if desired.

Claims

1. A method for dispensing a liquid from a pump, comprising:

providing a piston connected to a shape memory element;

providing a potential to the shape memory element in order to change the length of the element;

monitoring the position of the piston;

adjusting the potential applied to the shape memory element to move the piston and intake liquid, based upon the monitored position;

adjusting the potential applied to the shape memory element to move the piston and dispense liquid, based upon the monitored position;

measuring a first time period, wherein the first time period is the time it takes for the piston to complete an intake stroke;

comparing the first time period to a predetermined time period; and

determining that the pump is not primed when the first time period is below the predetermined time period by a threshold amount of time.

2. The method of claim 1 wherein providing a potential comprises applying pulses of potential and adjusting the potential comprises modulating the width of the applied pulses.

3. The method of claim 1 wherein monitoring the position comprises reading discrete position indicators.

4. The method of claim 1 wherein monitoring the position comprises measuring the variable output of an analog sensor.

5. The method of claim 1 wherein the determination that the pump is not primed is based upon a feedback response associated with the monitored position of the piston.

6. The method of claim 5 wherein the time it takes to complete the intake stroke includes an amount of time to move the piston from a first position to a second position.

7. The method of claim 6 wherein the predetermined time period is the expected amount of time it takes to move the piston from the first position to the second position.

8. The method of claim 1 further comprising generating a warning when the pump is not primed.

9. The method of claim 1 further comprising automatically priming a path for the dispensed liquid based on the rate of change of the position of the piston from a first position to a second position and a comparison between the monitored rate of change of the position of the piston and an expected rate of change of the position of the piston.

10. A method for dispensing liquid, comprising:

applying a potential to a shape memory alloy to cause a piston disposed within a chamber of a pump to move between a first position and a second position;

monitoring the position of the piston as the piston moves from the first position to the second position during an intake stroke and from the second position to the first position during discharge stroke;

measuring a first time period, wherein the first time period is the time it takes to move the piston from the first position to the second position during the intake stroke;

comparing the first time period to a predetermined time period; and

determining that the pump is not primed when the first time period is below the predetermined time period by a threshold amount of time.

11. The method of claim 10 wherein the position of the piston is monitored using a linear feedback mechanism.

12. The method of claim 10 further comprising detecting when the piston is at the first position and the second position using a plurality of switches.

13. The method of claim 12 wherein at least a first switch of the plurality of switches is disposed at a first physical limit defined by the chamber of the pump and wherein at least a second switch of the plurality of switches is disposed at a second physical limit defined by the chamber of the pump.

14. The method of claim 10 wherein the determination that the pump is not primed is based upon a feedback response associated with the monitored position of the piston.

15. The method of claim 14 wherein the feedback response includes an amount of time to complete a pumping cycle.

16. The method of claim 15 further comprising comparing the amount of time to complete the pumping cycle to an expected amount of time to complete the pumping cycle.

17. The method of claim 10 further comprising generating a warning when the pump is not primed.

18. The method of claim 10 further comprising measuring an amount of time to move the piston from the second position to the first position.

19. The method of claim 18 further comprising comparing the amount of time to move the piston from the second position to the first position with an expected amount of time to move the piston from the second position to the first position.

20. The method of claim 10 further comprising automatically priming a path for the dispensed liquid based upon at least one of a rate of change of the position of the piston from the first position to the second position and the rate of change of the position of the piston from the second position to the first position and a comparison between the monitored rate of change of the position of the piston and an expected rate of change of the position of the piston.