Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof

• US 8,034,450 B2
• Filed: 09/15/2005
• Issued: 10/11/2011
• Est. Priority Date: 01/21/2005
• Status: Active Grant

• Current Assignee: DSM Nutritional Products AG (DSM-Firmenich AG)
• Original Assignee: Ocean Nutrition Canada Limited (DSM-Firmenich AG)
• Inventors: Barrow, Colin James, Jin, Yulai, Curtis, Jonathan Michael, Zhang, Wei
• Primary Examiner(s): Seidleck; James J
• Assistant Examiner(s): Haider; Saira B
• Application Number:
  US11/227,961
• Publication Number:
  US 20060165990A1
• Time in Patent Office: 2,217 Days
• Field of Search: 428/402.2, 428/402.21, 428/403, 427/213.3, 264/4.1, 424/492, 424/489, 424/490, 514/963, 514/962
• US Class Current: 428/402.2
• CPC Class Codes: A23L 29/281 Proteins, e.g. gelatin or collagen
• CPC Class Codes: A23P 10/30 Encapsulation of particles, e.g. foodstuff additives
• CPC Class Codes: A23P 10/35 with oils, lipids, monoglycerides or diglycerides
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/224 Encapsulating agent
• CPC Class Codes: A23V 2250/1882 Polyunsaturated fatty acids
• CPC Class Codes: A23V 2250/5432 Gelatine
• CPC Class Codes: B01J 13/10 Complex coacervation, i.e. interaction of oppositely charged particles
• CPC Class Codes: Y10T 428/2984 Microcapsule with fluid core [includes liposome]
• CPC Class Codes: Y10T 428/2985 Solid-walled microcapsule from synthetic polymer
• CPC Class Codes: Y10T 428/2991 Coated

Abstract

Described herein are microcapsules and emulsions prepared from low Bloom gelatin and methods of making and using thereof.

Claims

1. A microcapsule comprising an agglomeration of primary microcapsules and a loading substance, each individual primary microcapsule having a primary shell, wherein the loading substance is encapsulated by the primary shell, wherein the agglomeration is encapsulated by an outer shell, wherein the primary shell and the outer shell are formed from a complex coacervate of a two-component system made from a no Bloom high molecular weight fish gelatin and a second polymer,

wherein the loading substance comprises an oil, a biologically active substance, or mixtures thereof;

wherein the microcapsule is crosslinked with an enzymatic crosslinker; and

wherein the loading substance is from 50% to 70% by weight of the microcapsule.

2. The microcapsule of claim 1, wherein the loading substance comprises an oil derived from an aquatic animal, plant or microorganism or a mixture thereof.

3. The microcapsule of claim 1, wherein the loading substance comprises a purified or partially purified fatty acid, triglyceride, ester, or mixtures thereof.

4. The microcapsule of claim 1, wherein the loading substance comprises a fish oil.

5. The microcapsule of claim 1, wherein the loading substance comprises an algal oil or fungal oil.

6. The microcapsule of claim 1, wherein the loading substance comprises one or more omega-3 fatty acids or mixtures or derivatives thereof.

7. The microcapsule of claim 1, wherein the loading substance comprises alpha-linolenic acid, stearidonic acid, eicosapentaenoic acid, docosahexaenoic acid, eicosatetraenoic acid, heneicosapentaenoic acid, docosapentaenoic acid or mixtures or derivatives thereof.

8. The microcapsule of claim 1, wherein the second polymer is polyphosphate and the dry weight ratio of the no Bloom fish gelatin to polyphosphate is about 8:

1 to about 12;

1.

9. The microcapsule of claim 1, wherein the second polymer is gelatin type B and the dry weight ratio of the no Bloom fish gelatin to gelatin type B is 2:

1 to 1;

2.

10. The microcapsule of claim 1, wherein the second polymer is alginate and the dry weight ratio of the no Bloom fish gelatin to alginate is 3:

1 to 20;

1.

11. The microcapsule of claim 1, wherein the primary and/or outer shell further comprises an antioxidant.

12. The microcapsule of claim 11, wherein the antioxidant is present in an amount of about 100 ppm to about 12,000 ppm.

13. The microcapsule of claim 1, wherein the primary and/or outer shell further comprises a metal chelator.

14. The microcapsule of claim 1, wherein the outer shell has an average diameter of from about 20 μ

m to about 100 μ

m.

15. The microcapsule of claim 1, wherein the primary shell has an average diameter of from about 40 nm to about 10 μ

m.

16. The microcapsule of claim 1, wherein the primary shell has an average diameter of from about 0.1 μ

m to about 10 μ

m.

17. The microcapsule of claim 1, wherein the primary shell has an average diameter of from about 1 μ

m to about 6 μ

m.

18. The microcapsule of claim 1, wherein the enzymatic crosslinker is transglutaminase.

19. The microcapsule of claim 1, wherein the microcapsule is spray-dried.

20. The microcapsule of claim 1, wherein the microcapsule further comprises ascorbic acid or a salt thereof.