Non-invasive blood pressure determination method

• US 8,047,998 B2
• Filed: 04/17/2007
• Issued: 11/01/2011
• Est. Priority Date: 04/17/2007
• Status: Active Grant

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Hersh, Lawrence T., Kolluri, Sai, Friedman, Bruce A.
• Primary Examiner(s): Marmor, II; Charles A
• Assistant Examiner(s): TRAN, THO Q
• Application Number:
  US11/736,276
• Publication Number:
  US 20080262362A1
• Time in Patent Office: 1,659 Days
• Field of Search: 600/494, 600/485, 600/486, 600/487, 600/490, 600/496, 600/493, 600/492, 600/491, 600/488
• US Class Current: 600/494
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/0285 Measuring or recording phase velocity of blood waves
• CPC Class Codes: A61B 5/14551 for measuring blood gases

Abstract

A method for estimating systolic and diastolic pressure is disclosed herein. The method includes obtaining a predetermined type of blood pressure data from a patient, and providing previously acquired blood pressure data obtained from a plurality of different subjects. The method also includes implementing the previously acquired blood pressure data to select systolic and diastolic amplitude ratios that most closely correlate with the predetermined type of blood pressure data obtained from the patient. The selected systolic and diastolic amplitude ratios are adapted to compensate for the effects of arterial compliance. The method also includes implementing the selected systolic and diastolic amplitude ratios to generate a systolic and diastolic blood pressure estimates.

Claims

1. A method for estimating systolic blood pressure and diastolic blood pressure comprising:

obtaining a pulse transit time slope from a patient;

providing previously acquired blood pressure data obtained from a plurality of different subjects to a processor, said previously acquired blood pressure data adapted to convey the manner in which a systolic amplitude ratio and a diastolic amplitude ratio vary with respect to the pulse transit time slope obtained from the patient;

implementing the previously acquired blood pressure data in the processor to select a systolic amplitude ratio and a diastolic amplitude ratio that most closely correlate with the pulse transit time slope obtained from the patient, wherein the selected systolic amplitude ratio and diastolic amplitude ratio are adapted to compensate for the effects of arterial compliance;

implementing the selected systolic amplitude ratio in the processor to estimate a systolic blood pressure level; and

implementing the selected diastolic amplitude ratio in the processor to estimate a diastolic blood pressure level.

2. The method of claim 1, wherein said obtaining a predetermined type of blood pressure data includes implementing a non-invasive blood pressure monitor and a pulse oximeter device.

3. The method of claim 1, wherein said obtaining the pulse transit time slope includes obtaining at least two pulse transit times from the patient.

4. The method of claim 1, wherein said providing previously acquired blood pressure data obtained from the plurality of different subjects includes providing the previously acquired blood pressure data in the form of an equation.

5. The method of claim 1, wherein said providing previously acquired blood pressure data obtained from the plurality of different subjects includes providing the previously acquired blood pressure data in the form of a table.

6. A method for estimating systolic blood pressure and diastolic blood pressure comprising:

providing a non-invasive blood pressure monitor comprising a cuff configured to apply a selectable pressure level to a patient;

estimating a first pulse transit time in a processor at a first cuff pressure level, and estimating a second pulse transit time in the processor at a second cuff pressure level;

calculating a pulse transit time ratio in the processor defined as the first pulse transit time divided by the second pulse transit time;

providing blood pressure data in the processor adapted to correlate a plurality of pulse transit time ratios with a plurality of systolic amplitude ratios and a plurality of diastolic amplitude ratios;

selecting one of the plurality of systolic amplitude ratios and one of the plurality of diastolic amplitude ratios that most closely correlate with the calculated pulse transit time ratio, wherein the selected systolic amplitude ratio and the selected diastolic amplitude ratio are adapted to compensate for the effects of arterial compliance;

implementing the selected systolic amplitude ratio in the processor to estimate a systolic blood pressure level; and

implementing the selected diastolic amplitude ratio in the processor to estimate a diastolic blood pressure level.

7. The method of claim 6, further comprising providing a pulse oximeter device operatively configured for connection to a patient.

8. The method of claim 7, wherein said estimating a first pulse transit time comprises:

identifying a pulse at a first location within the patient using the non-invasive blood pressure monitor;

identifying said pulse at a second location within the patient using the pulse oximeter device; and

measuring the elapsed time between the identification of the pulse at the first location and the identification of the pulse at the second location.

9. The method of claim 6, wherein said providing blood pressure data includes providing multiple blood pressure measurements taken from a plurality of different subjects.

10. The method of claim 9, wherein said providing blood pressure data includes providing blood pressure data acquired with an intra-arterial procedure, an auscultatory procedure, and/or an oscillometric procedure.

11. The method of claim 9, wherein said providing blood pressure data includes providing the blood pressure data in the form of an equation.

12. The method of claim 9, wherein said providing blood pressure data includes providing the blood pressure data in the form of a table.

13. A method for estimating systolic blood pressure and diastolic blood pressure comprising:

estimating a pulse wave velocity in a processor of a pulse being transmitted through a patient;

providing blood pressure data in the processor adapted to correlate a plurality of pulse wave velocity values with a plurality of systolic amplitude ratios and a plurality of diastolic amplitude ratios;

selecting one of the plurality of systolic amplitude ratios and one of the plurality of diastolic amplitude ratios that are most closely correlated with the estimated pulse wave velocity, wherein the selected systolic amplitude ratio and the selected diastolic amplitude ratio are adapted to compensate for the effects of arterial compliance;

implementing the selected systolic amplitude ratio in the processor to estimate a systolic blood pressure level; and

implementing the selected diastolic amplitude ratio in the processor to estimate a diastolic blood pressure level.

14. The method of claim 13, wherein said estimating a pulse wave velocity includes implementing a non-invasive blood pressure monitor and pulse oximeter device to estimate the pulse wave velocity.

15. The method of claim 14, wherein said estimating a pulse wave velocity includes:

identifying the pulse at a first location within the patient using the non-invasive blood pressure monitor;

identifying the pulse at a second location within the patient using the pulse oximeter device;

estimating the distance between the first location and the second location;

estimating a pulse transit time comprising the time required for said pulse to travel from the first location and the second location; and

dividing the distance by the pulse transit time.

16. The method of claim 13, wherein said providing blood pressure data includes providing multiple blood pressure measurements taken from a plurality of different subjects.

17. The method of claim 16, wherein said providing blood pressure data includes providing blood pressure data acquired with an intra-arterial procedure, an auscultatory procedure, and/or an oscillometric procedure.

18. The method of claim 16, wherein said providing blood pressure data includes providing the blood pressure data in the form of an equation.

19. The method of claim 16, wherein said providing blood pressure data includes providing the blood pressure data in the form of a table.