Pharmaceutical composition

CAFC
  • US 8,063,029 B2
  • Filed: 10/31/2007
  • Issued: 11/22/2011
  • Est. Priority Date: 04/19/2002
  • Status: Active Grant
First Claim
Patent Images

1. A method for maintaining a therapeutically effective concentration of testosterone in the blood serum of a male for treating hypogonadism which comprises transdermally delivering to the male by applying to the skin a composition which is in the form of a topical gel, which has a viscosity of about 500 to about 20,000 cps and a pH of about 3 to about 9, and comprises:

  • (A) about 0.1 to about 5 wt. % of testosterone;

    (B) about 0.5 to about 25 wt. % of a Hsieh enhancer;

    (C) about 0.1 to about 10 wt. % of a thickening agent; and

    (D) a mixture of solvents which include about 40 to about 80 wt. % of lower alkanol;

    wherein the Hsieh enhancer is selected from the group consisting of 3-methylcyclopentadecanone, 9-cycloheptadecen-1-one, cyclohexadecanone, cyclopentadecanone and oxacyclohexadecan-2-one.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×