Systems and methods for transmitting pathogen related information and responding

• US 8,068,991 B2
• Filed: 09/11/2007
• Issued: 11/29/2011
• Est. Priority Date: 11/30/2005
• Status: Active Grant

• Current Assignee: Inflammatix, Inc.
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Wood, Lowell L. Jr., Lord, Robert W., Levien, Royce A., Jung, Edward K. Y., Malamud, Mark A., Rinaldo, John D. Jr., Leuthardt, Eric C.
• Primary Examiner(s): ZEMAN, MARY K
• Application Number:
  US11/900,660
• Publication Number:
  US 20080183396A1
• Time in Patent Office: 1,540 Days
• Field of Search: None
• US Class Current: 702/19
• CPC Class Codes: B01L 3/5027 by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip B01L3/5023 takes precedence; micromixers B01F33/30; microreactors for synthesis B01J19/0093; microcapillary devices in general B81B1/00
• CPC Class Codes: G01N 2035/00158 Elements containing microarrays, i.e. "biochip"
• CPC Class Codes: G01N 33/5302 Apparatus specially adapted for immunological test procedures
• CPC Class Codes: G01N 33/54326 Magnetic particles
• CPC Class Codes: G01N 33/569 for microorganisms, e.g. protozoa, bacteria, viruses
• CPC Class Codes: G01N 35/00029 provided with flat sample substrates, e.g. slides G01N35/028 takes precedence
• CPC Class Codes: G06F 21/6245 Protecting personal data, e.g. for financial or medical purposes
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 70/60 relating to pathologies
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

The present disclosure relates to methods and systems that may be used for detection of one or more pathogens and determining one or more agents in response to pathogen detection.

Claims

1. A method comprising:

receiving data identifying one or more pathogens present within one or more samples obtained from an individual through use of one or more microfluidic chips;

receiving input associated with the individual from whom the one or more samples were obtained, the input including at least one of;

one or more physical characteristics, medical history information, one or more activities, and/or substance usage information associated with the individual; and

processing, using one or more processing devices, the input associated with the individual and the data identifying the one or more pathogens by at least determining versus time one or more values associated with the one or more pathogens and one or more values associated with agent usage by the one or more individuals;

determining whether at least one relationship exists between the agent usage and the one or more pathogens; and

determining based at least in part upon at least one determined relationship one or more agents or agent dosages.

2. The method of claim 1, wherein the receiving data identifying one or more pathogens present within one or more samples obtained from an individual through use of one or more microfluidic chips comprises:

receiving data identifying one or more pathogens from one or more analysis units operably associated with one or more microfluidic chips.

3. The method of claim 1, further comprising:

transmitting one or more signals that include information associated with the data identifying one or more pathogens.

4. The method of claim 1, further comprising:

receiving one or more signals that include information associated with the one or more agents.

5. The method of claim 4, wherein the receiving one or more signals that include information associated with the one or more agents comprises:

receiving one or more signals that include information associated with contraindicators of the one or more agents.

6. The method of claim 4, wherein the receiving one or more signals that include information associated with the one or more agents comprises:

receiving one or more signals that include information associated with side-effects of the one or more agents.

7. The method of claim 4, further comprising:

displaying the information associated with the one or more agents.

8. The method of claim 7, wherein the displaying the information associated with the one or more agents comprises:

displaying the information in Braille.

19. The method of claim 1, wherein the receiving input associated with the individual from whom the one or more samples were obtained comprises:

receiving input associated with the individual via a user interface of a handheld portable device operably couplable with the one or more microfluidic chips.

20. The method of claim 1, further comprising:

determining one or more personalized release rates of the one or more agents using the input associated with the individual.

21. The method of claim 1, further comprising:

transmitting one or more signals that include at least one order for the one or more agents.

22. The method of claim 1, further comprising:

transmitting one or more signals that include at least one order for two or more agents in single administration form.

23. The method of claim 1, further comprising:

determining treatment effectiveness by receiving data associated with the one or more pathogens following consumption of the one or more agents.

24. The method of claim 7, wherein the displaying the information associated with the one or more agents comprises:

displaying the information in audio form.

25. The method of claim 1, wherein the processing, using one or more processing devices, the input associated with the individual and the data identifying the one or more pathogens by at least determining versus time one or more values associated with the one or more pathogens and one or more values associated with agent usage by the one or more individuals;

determining whether at least one relationship exists between the agent usage and the one or more pathogens; and

determining based at least in part upon at least one determined relationship one or more agents or agent dosages comprises;

processing, using one or more processing devices, the input associated with the individual and the data identifying the one or more pathogens by at least determining versus time one or more values associated with the one or more pathogens, at least one value of which is determined from the input associated with the individual, and one or more values associated with agent usage by the one or more individuals;

determining whether at least one relationship exists between the agent usage and the one or more pathogens; and

determining based at least in part upon at least one determined relationship one or more agents or agent dosages.

26. The method of claim 1, further comprising:

transmitting one or more signals that include information associated with the one or more agents or agent dosages.

9. A system comprising:

a non-transitory signal-bearing medium bearing;

one or more instructions for receiving data identifying one or more pathogens present within one or more samples obtained from an individual through use of one or more microfluidic chips;

one or more instructions for receiving input associated with the individual from whom the one or more samples were obtained, the input including at least one of;

one or more physical characteristics, medical history information, one or more activities, and/or substance usage information associated with the individual; and

one or more instructions for processing the input associated with the individual and the data identifying the one or more pathogens by at least determining versus time one or more values associated with the one or more pathogens and one or more values associated with agent usage by the one or more individuals;

determining whether at least one relationship exists between the agent usage and the one or more pathogens; and

determining based at least in part upon at least one determined relationship one or more agents or agent dosages.

10. The system of claim 9, further comprising:

one or more instructions for receiving one or more signals that include information associated with the one or more agents.

11. The system of claim 10, further comprising:

one or more instructions for displaying the information associated with the one or more agents.

12. A system comprising:

circuitry for receiving data identifying one or more pathogens present within one or more samples obtained from an individual through use of one or more microfluidic chips;

circuitry for receiving input associated with the individual from whom the one or more samples were obtained, the input including at least one of;

one or more physical characteristics, medical history information, one or more activities, and/or substance usage information associated with the individual; and

circuitry for processing the input associated with the individual and the data identifying the one or more pathogens by at least determining versus time one or more values associated with the one or more pathogens and one or more values associated with agent usage by the one or more individuals;

determining whether at least one relationship exists between the agent usage and the one or more pathogens; and

determining based at least in part upon at least one determined relationship one or more agents or agent dosages.

13. The system of claim 12, wherein the circuitry for receiving data identifying one or more pathogens present within one or more samples obtained from an individual through use of one or more microfluidic chips comprises:

circuitry for receiving data identifying one or more pathogens from one or more analysis units operably associated with one or more microfluidic chips.

14. The system of claim 12, further comprising:

circuitry for transmitting one or more signals that include information associated with the data identifying one or more pathogens.

15. The system of claim 12, further comprising:

circuitry for receiving one or more signals that include information associated with the one or more agents.

16. The system of claim 15, further comprising:

circuitry for displaying the information associated with the one or more agents.

17. The system of claim 16, wherein the circuitry for displaying the information associated with the one or more comprises:

circuitry for displaying the information in audio form.

18. The system of claim 16, wherein the circuitry for displaying the information associated with the one or more agents comprises:

circuitry for displaying the information in Braille.

27. The system of claim 12, further comprising:

circuitry for transmitting one or more signals that include at least one order for the one or more agents.

28. The system of claim 12, further comprising:

circuitry for determining treatment effectiveness by receiving data associated with the one or more pathogens following consumption of the one or more agents.

29. The system of claim 12, wherein the circuitry for processing the input associated with the individual and the data identifying the one or more pathogens by at least determining versus time one or more values associated with the one or more pathogens and one or more values associated with agent usage by the one or more individuals;

determining whether at least one relationship exists between the agent usage and the one or more pathogens; and

determining based at least in part upon at least one determined relationship one or more agents or agent dosages comprises;

circuitry for processing the input associated with the individual and the data identifying the one or more pathogens by at least determining versus time one or more values associated with the one or more pathogens, at least one value of which is determined from the input associated with the individual, and one or more values associated with agent usage by the one or more individuals;

determining whether at least one relationship exists between the agent usage and the one or more pathogens; and

determining based at least in part upon at least one determined relationship one or more agents or agent dosages.

30. The system of claim 12, further comprising:

circuitry for transmitting one or more signals that include information associated with the one or more agents or agent dosages.