Systems and methods for intra-oral drug delivery
First Claim
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1. A method for delivering one or more substances, comprising:
- providing a dental device comprising a shell formed of a material and the dental device configured to move a number of teeth and including one or more reservoirs formed in the shell;
supplying at least one of the reservoirs with the one or more substances;
fluidly releasing the one or more substances from at least one reservoir into a gum of a patient via a nozzle formed of the material as a portion of the shell and connected to the at least one reservoir and inserted into the gum at a first preselected dose at a first predetermined time period, wherein the nozzle is shaped to conform to the gum for prolonged placement therein; and
fluidly releasing the one or more substances from at least one reservoir into the gum via a nozzle connected to the at least one reservoir and inserted into the gum at a second preselected dose at a second predetermined time period.
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Abstract
Systems and methods are disclosed for intra-oral delivery of drugs. One method embodiment includes providing a dental device with one or more reservoirs, supplying at least one of the reservoirs with the one or more substances, and fluidly releasing the one or more substances from at least one reservoir into an oral structure at different preselected doses at different predetermined time periods and in a predetermined sequence.
260 Citations
24 Claims
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1. A method for delivering one or more substances, comprising:
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providing a dental device comprising a shell formed of a material and the dental device configured to move a number of teeth and including one or more reservoirs formed in the shell;
supplying at least one of the reservoirs with the one or more substances;
fluidly releasing the one or more substances from at least one reservoir into a gum of a patient via a nozzle formed of the material as a portion of the shell and connected to the at least one reservoir and inserted into the gum at a first preselected dose at a first predetermined time period, wherein the nozzle is shaped to conform to the gum for prolonged placement therein; andfluidly releasing the one or more substances from at least one reservoir into the gum via a nozzle connected to the at least one reservoir and inserted into the gum at a second preselected dose at a second predetermined time period. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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Specification