Diclofenac formulations and methods of use

  • US 8,097,651 B2
  • Filed: 01/07/2010
  • Issued: 01/17/2012
  • Est. Priority Date: 06/17/2005
  • Status: Active Grant
First Claim
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1. A method of treating phonophobia and photophobia in a human patient in need thereof comprising:

  • a) providing an oral formulation comprising one or more pharmaceutically acceptable excipients and 50 mg. of diclofenac or a pharmaceutically acceptable salt thereof, wherein said one or more pharmaceutically acceptable excipients comprises a buffering or alkalizing agent, further wherein said formulation has been shown to achieve a Cmax of from about 1500 to about 2500 ng/ml and tmax in from about 10 to about 25 minutes; and

    b) orally administering said formulation to a patient suffering from phonophobia and photophobia wherein said tmax and Cmax are mean values obtained from a plurality of human patients.

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