Abuse-proofed dosage form

CAFC
  • US 8,114,383 B2
  • Filed: 11/20/2003
  • Issued: 02/14/2012
  • Est. Priority Date: 08/06/2003
  • Status: Active Grant
First Claim
Patent Images

1. A thermoformed dosage form comprising:

  • i) one or more active ingredients with abuse potential (A) selected from the group consisting of opiates and opioids,ii) optionally physiologically acceptable auxiliary substances (B),iii) at least 30% by weight of polyalkylene oxide (C) having a molecular weight of 1-15 million according to rheological measurements, andiv) optionally at least one wax (D),wherein said dosage form has a breaking strength of at least 500 N and wherein the active ingredient with abuse potential (A) is present in a controlled release matrix of component (C).

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