Targeted muscle ablation for reducing signs of aging

• US 8,128,618 B2
• Filed: 08/03/2006
• Issued: 03/06/2012
• Est. Priority Date: 08/03/2005
• Status: Active Grant

• Current Assignee: Massachusetts Eye And Ear Infirmary (Foundation of The Massachusetts Eye and EAR Infirmary Incorporated)
• Original Assignee: Massachusetts Eye And Ear Infirmary (Foundation of The Massachusetts Eye and EAR Infirmary Incorporated)
• Inventors: Gliklich, Richard E., White, William Matthew
• Primary Examiner(s): Dvorak, Linda
• Assistant Examiner(s): SCOTT, AMANDA L
• Application Number:
  US11/462,191
• Publication Number:
  US 20070032784A1
• Time in Patent Office: 2,042 Days
• Field of Search: 606 27- 32
• US Class Current: 606/27
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 8/4411 Device being modular
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

A method and system for delivering energy to affect the signs of aging is described. Energy is delivered to a target volume of a muscle such that the energy creates a lesion in the target volume. A characteristic of the lesion is controlled to affect movement of the muscle.

Claims

1. A method for removing wrinkles in a subject'"'"'s forehead, the method comprising:

producing a map of a forehead muscle of the subject;

using the map, locating a target volume of the forehead muscle, wherein the target volume is between about 2 mm and about 12 mm below an epidermal surface of the subject; and

delivering energy to the target volume at a power, a frequency, and for a time selected such that the energy creates a pattern of lesions in the target volume, the pattern selected to achieve a desired degree of paralysis of the muscle, wherein each of the lesions in the pattern is confined within the target volume and the delivered energy does not significantly damage tissue surrounding the target volume.

2. The method of claim 1, further comprising selecting a characteristic of the lesion to paralyze the muscle.

3. The method of claim 2, wherein the characteristic comprises at least one of:

a size, a shape, a depth below the epidermal surface, and a location relative to another lesion.

4. The method of claim 1, wherein delivering energy comprises selecting the energy to be ultrasound.

5. The method of claim 1, wherein delivering energy comprises selecting the energy to be radio frequency electromagnetic energy.

6. The method of claim 1, wherein the selected frequency is within a range of 4 to 8 MHz;

and the selected power is within a range of 60 to 80 W.

7. The method of claim 1, wherein producing the map comprises acquiring an echo image of the muscle from echoes generated by reflections of ultrasound pulses directed towards the muscle.

8. The method of claim 1, further comprising selecting the pattern to be one of:

a square, triangle, polygon, grid, criss-cross pattern, circle, oval, and coil.

9. The method of claim 1, further comprising selecting the pattern to be a matrix of lesions spaced approximately equidistant from each other.

10. The method of claim 9, further comprising:

selecting the lesions to be approximately 1 mm³ in volume; and

selecting spacings between the lesions to be approximately 1 mm.

11. The method of claim 1, wherein the forehead muscle includes at least one of a corrugator, a procerus, and a frontalis muscle.

12. The method of claim 1, wherein delivering the energy to the target volume further comprises focusing the energy into the target volume.