Methods and compositions for tissue regeneration
First Claim
Patent Images
1. A kit comprising:
- (a) a first component comprising alginate, wherein the first component is comprised in a first sterile vial; and
(b) a second component comprising;
cells comprising keratinocytes or fibroblasts, or mixtures thereof, that secrete one or more biologically active molecules selected from the group consisting of GM-CSF, VEGF, KGF, bFGF, TGFβ
, angiopoietin, EGF, IL-Iβ
, IL-6, IL-8, TGFα
, and TNFα
, wherein the cells are allogeneic and mitotically inactive;
a buffered solution; and
human serum albumin or a cryoprotectant,wherein the second component is comprised in a second sterile vial.
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Abstract
A kit is disclosed that includes a first component comprising alginate, wherein the first component is comprised in a first sterile vial, and a second component comprising cells comprising keratinocytes or fibroblasts, or mixtures thereof, that secrete one or more biologically active molecules selected from the group consisting of GM-CSF, VEGF, KGF, bFGF, TGFβ, angiopoietin, EGF, IL-Iβ, IL-6, IL-8, TGFα, and TNFα, wherein the cells are allogeneic and mitotically inactive, a buffered solution, and human serum albumin or a cryoprotectant, wherein the second component is comprised in a second sterile vial.
30 Citations
14 Claims
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1. A kit comprising:
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(a) a first component comprising alginate, wherein the first component is comprised in a first sterile vial; and (b) a second component comprising; cells comprising keratinocytes or fibroblasts, or mixtures thereof, that secrete one or more biologically active molecules selected from the group consisting of GM-CSF, VEGF, KGF, bFGF, TGFβ
, angiopoietin, EGF, IL-Iβ
, IL-6, IL-8, TGFα
, and TNFα
, wherein the cells are allogeneic and mitotically inactive;a buffered solution; and human serum albumin or a cryoprotectant, wherein the second component is comprised in a second sterile vial. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification