Method for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
First Claim
1. A method of blocking undesirable side effect activation of electrically excitable tissue, the method comprising the steps of:
- therapeutically activating tissue at a first predetermined site within a patient'"'"'s body; and
blocking activation of tissue or conduction of action potentials at a second predetermined site within the patient'"'"'s body by applying high frequency stimulation or one or more direct current pulses or both high frequency stimulation and one or more direct current pulses at or near the second site, wherein the undesired effect is muscle contraction;
the desired effect is peristalsis of the patient'"'"'s ureter; and
the undesired side effect is closure of the patient'"'"'s anti-reflux valves near the patient'"'"'s bladder trigone.
0 Assignments
0 Petitions
Accused Products
Abstract
A desired effect is produced by therapeutically activating tissue at a first site within a patient'"'"'s body and a corresponding undesired side effect is reduced by blocking activation of tissue or conduction of action potentials at a second site within the patient'"'"'s body by applying high frequency stimulation and/or direct current pulses at or near the second site. Time-varying DC pulses may be used before or after a high frequency blocking signal. The high frequency stimulation may begin before and continue during the therapeutic activation. The high frequency stimulation may begin with a relatively low amplitude, and the amplitude may be gradually increased. The desired effect may be promotion of micturition or defecation and the undesired side effect may be sphincter contraction.
4 Citations
9 Claims
-
1. A method of blocking undesirable side effect activation of electrically excitable tissue, the method comprising the steps of:
-
therapeutically activating tissue at a first predetermined site within a patient'"'"'s body; and blocking activation of tissue or conduction of action potentials at a second predetermined site within the patient'"'"'s body by applying high frequency stimulation or one or more direct current pulses or both high frequency stimulation and one or more direct current pulses at or near the second site, wherein the undesired effect is muscle contraction; the desired effect is peristalsis of the patient'"'"'s ureter; and the undesired side effect is closure of the patient'"'"'s anti-reflux valves near the patient'"'"'s bladder trigone. - View Dependent Claims (2, 3)
-
-
4. A method of blocking undesirable side effect activation of electrically excitable tissue, wherein such undesirable side effect activation includes muscle contraction, the method comprising the steps of:
-
therapeutically activating tissue at a first predetermined site within a patient'"'"'s body by applying low frequency stimulation at or near the first predetermined site; and blocking activation of tissue or conduction of action potentials at a second predetermined site within the patient'"'"'s body by applying high frequency stimulation or one or more direct current pulses or both high frequency stimulation and one or more direct current pulses at or near the second site such that the high frequency stimulation and/or the direct current pulses prevent the low frequency stimulation applied at the first site from activating the electrically excitable tissue, or causing conduction of action potentials, at the second site, wherein; the desired effect is peristalsis of the patient'"'"'s ureter and the first site is selected from the group consisting of the patient'"'"'s;
renal pelvis and a portion of the patient'"'"'s ureter; andthe undesired side effect is closure of the patient'"'"'s anti-reflux valves near the patient'"'"'s bladder trigone and the second site is the base of the patient'"'"'s bladder near an entrance of the ureter, hypogastric plexus, and pelvic plexus. - View Dependent Claims (5, 6, 7, 8, 9)
-
Specification