Satiation devices and methods

• US 8,177,853 B2
• Filed: 09/28/2011
• Issued: 05/15/2012
• Est. Priority Date: 08/27/2001
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Barosense, Inc. (Boston Scientific Corporation)
• Inventors: Stack, Richard S., Glenn, Richard A., Moody, Trevor J., Silverstein, Fred E., Every, Nathan, Eubanks, William S. Jr.
• Primary Examiner(s): Willse, David H
• Assistant Examiner(s): BLANCO, JAVIER G
• Application Number:
  US13/247,400
• Publication Number:
  US 20120016287A1
• Time in Patent Office: 230 Days
• Field of Search: 623/23.65, 623/23.7, 604/8
• US Class Current: 623/23.7
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/24 Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
• CPC Class Codes: A61F 2002/044 Oesophagi or esophagi or gullets
• CPC Class Codes: A61F 2002/045 Stomach, intestines
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 5/0069 in the wall of the stomach
• CPC Class Codes: A61F 5/0076 preventing normal digestion, e.g. Bariatric or gastric sleeves
• CPC Class Codes: A61F 5/0079 Pyloric or esophageal obstructions

Abstract

A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

Claims

1. A method for treating obesity in a patient, the method comprising

providing an intestinal sleeve device comprising an elongate polymeric sleeve at least 20 cm in length and extending between proximal and distal open ends, and an expandable wire structure disposed entirely within the sleeve, the expandable wire structure being adapted, in its expanded form, to press against the walls of the intestine,

passing the entire intestinal sleeve device in a distal direction through the patient'"'"'s esophagus and into the small intestine of the patient;

positioning within the small intestine of the patient said intestinal sleeve device, with said expandable wire structure adapted, in its expanded form, and with the device positioned entirely within the small intestine of the patient, to anchor the device within the patient'"'"'s duodenum, by pressing the sleeve against the wall of the intestine, and

with the sleeve device positioned entirely within the small intestine of the patient, expanding the expandable wire structure in the device, thereby anchoring the sleeve device within the duodenum of the intestine, and allowing food from the stomach to flow through the intestinal sleeve device within the duodenum while preventing absorption of food through the walls of the duodenum,

wherein the sleeve device is anchored entirely within the duodenum,

wherein the wire structure in the sleeve device is self-expanding, and said expanding includes allowing the wire structure to self expand, thereby pressing the device against the walls of the duodenum, and

wherein the outer surface of the sleeve is provided with surface features to prevent movement of the device within the duodenum.

2. The method of claim 1, wherein the sleeve device is anchored within the duodenum with its proximal end adjacent, and at least one centimeter downstream of, the ampulla of vader.

3. The method of claim 1, wherein the self-expanding wire structure is formed of nitinol.

4. The method of claim 1, wherein the sleeve device is anchored within the duodenum of the intestine by an expandable wire structure that includes an expandable ring.

5. The method of claim 4, wherein the expandable wire structure includes a plurality of rings spaced along the length of the sleeve device.

6. The method of claim 1, wherein the sleeve device is anchored within the duodenum of the intestine by an expandable wire structure that includes helical ridges.

7. The method of claim 6, wherein helical ridges in the expandable wire structure extend along the length of the sleeve device.