Methods of treating medical conditions by neuromodulation of the cerebellar pathways
First Claim
1. A system for improving a medical condition resulting from a stroke or a traumatic etiology in a patient suffering therefrom comprising:
- a therapy delivery device for positioning on at least one target site selected from the group consisting of a deep cerebellar target site;
a thalamic nucleus target site that is within the cerebello-thalamo-cortical pathway and thus receives a projection from a deep cerebellar nucleus and projects to the cerebral cortex; and
projections from the cerebellum to the thalamus; and
a controller in communication with the therapy delivery device and programmed with stimulation parameters suitable for delivering a therapy signal to the target site to improve the medical condition resulting from the stroke or the traumatic etiology in the patient.
0 Assignments
0 Petitions
Accused Products
Abstract
Methods of treating various medical conditions by neuromodulation of target sites of a cerebello-thalamo-cortical pathway and/or a cortical-ponto-cerebellar pathway. Such medical conditions include unilateral motor deficits, movement disorders, psychiatric disorders, epilepsy, speech or cognitive deficits associated with hemispheric lesions, visual deficits associated with hemispheric lesions, learning disorders associated with hemispheric lesions, vertigo and/or dizziness, gait disturbances, hereditary/genetic disorders, congenital malformations, infectious disease, degenerative disorders, autoimmune disorders, and metabolic disorders. A method of enhancing memory, learning and/or cognitive capacity in a normal individual by stimulating a target site of a cerebello-thalamo-cortical pathway and/or a cortical-ponto-cerebellar pathway is also provided.
9 Citations
14 Claims
-
1. A system for improving a medical condition resulting from a stroke or a traumatic etiology in a patient suffering therefrom comprising:
-
a therapy delivery device for positioning on at least one target site selected from the group consisting of a deep cerebellar target site;
a thalamic nucleus target site that is within the cerebello-thalamo-cortical pathway and thus receives a projection from a deep cerebellar nucleus and projects to the cerebral cortex; and
projections from the cerebellum to the thalamus; anda controller in communication with the therapy delivery device and programmed with stimulation parameters suitable for delivering a therapy signal to the target site to improve the medical condition resulting from the stroke or the traumatic etiology in the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
-
-
14. A system for improving a medical condition resulting from a stroke or a traumatic etiology in a patient suffering therefrom comprising:
-
a therapy delivery device for applying a therapy signal on at least one target site selected from the group consisting of a deep cerebellar target site;
a thalamic nucleus target site that is within the cerebello-thalamo-cortical pathway and thus receives a projection from a deep cerebellar nucleus and projects to the cerebral cortex; and
projections from the cerebellum to the thalamus; anda sensor for detecting a bodily activity indicative of the presence or severity of the medical condition resulting from the stroke or the traumatic etiology and for generating a sensor signal; and a controller in communication with the therapy delivery device and the sensor and programmed with stimulation parameters suitable to activate the therapy delivery device to initiate application of the therapy signal to the target site or to adjust application of the therapy signal to the target site in response to the sensor signal to improve the medical condition resulting from the stroke or the traumatic etiology in the patient.
-
Specification