Fluid cartridges and partially implantable medical devices for use with same

• US 8,197,454 B2
• Filed: 02/21/2009
• Issued: 06/12/2012
• Est. Priority Date: 02/21/2009
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: IncuMED, LLC
• Inventors: Mann, Alfred E., He, Tom Xiaohai
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): Bosworth, Kami A
• Application Number:
  US12/390,432
• Publication Number:
  US 20100217241A1
• Time in Patent Office: 1,207 Days
• Field of Search: 604/65, 604/67, 604/274, 60428801-28804, 604/890.1, 604/891.1, 604 39- 45, 604/132, 604/175, 604/116, 604/117, 604/189
• US Class Current: 604/288.04
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/6054 Magnetic identification systems
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 39/0247 Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body peritoneal dialysis catheters A61M1/285; tracheostomy devices A61M16/0465; measuring pressure within the body A61B5/03; colostomy devices A61F5/445; gastrotomy feeding tubes A61J15/0015; means for fixing a feeding tube outside of the body A61J15/0053
• CPC Class Codes: A61M 39/04 having pierceable self-sealing members
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16854 by monitoring line pressure

Abstract

A fluid cartridge including a housing, a needle extending from the housing and a plurality of circumferentially spaced sensible members carried by the housing such that each of the sensible members is circumferentially spaced from the other sensible members, and apparatus including such a cartridge in combination with a partially implantable medical device.

Claims

1. A fluid cartridge, comprising:

a housing including a substantially cylindrical side wall and an end wall and defining a longitudinal axis and an internal volume;

a needle that extends from the end wall and is not movable relative to the end wall; and

a plurality of substantially flat electrically conductive sensible members that are not electrically connected to power that flows through other electrically conductive structure on the housing, that are mounted directly on the housing end wall such that each of the sensible members is offset from the other sensible members in a circumferential direction that extends around the longitudinal axis and that are separated from one another by electrically non-conductive regions.

2. A fluid cartridge as claimed in claim 1, further comprising:

a bladder located within the housing and having an outer surface and an inner surface, the inner surface defining a fluid storage volume having a full state that is substantially equal to the internal volume of the housing.

3. A fluid cartridge as claimed in claim 2, wherein the bladder includes a substantially cylindrical side wall and an end wall, and the substantially cylindrical side wall of the bladder is secured directly to the substantially cylindrical side wall of the housing.

4. A fluid cartridge as claimed in claim 3, wherein

the housing substantially cylindrical side wall includes an aperture and an external ring that is located between the aperture and the end wall from which the needle extends;

and

the bladder is configured such that the outer surface of the bladder substantially cylindrical side wall abuts the aperture when the fluid storage volume is in the full state.

5. A fluid cartridge as claimed in claim 1, wherein the needle comprises a non-coring needle.

6. A fluid cartridge as claimed in claim 1, wherein the needle defines a longitudinal axis that is substantially coaxial with the housing longitudinal axis.

7. A fluid cartridge as claimed in claim 1, wherein the plurality of sensible members are carried on the exterior of the housing.

8. A fluid cartridge as claimed in claim 1, further comprising:

a drug within the housing.

9. A fluid cartridge as claimed in claim 1, wherein the sensible members comprise first, second and third sensible members.

10. A fluid cartridge as claimed in claim 9, wherein spacing between the first and second sensible members is equal to spacing between the second and third sensible members.

11. A fluid cartridge as claimed in claim 1, wherein the sensible members are not needles.

12. An apparatus for use with an epidermis, comprising:

a fluid cartridge including a housing with a substantially cylindrical side wall and an end wall, a needle extending from the housing end wall, and at least one sensible member mounted directly on the housing end wall; and

a partially implantable medical device including

a percutaneous port configured to receive the fluid cartridge such that at least a portion of the fluid cartridge housing extends through the epidermis and to permit the fluid cartridge to be rotated from outside the percutaneous port and to be removed from the epidermis independently of the percutaneous port,

an implantable operative portion including a fluid transfer device, and

a sensor for sensing the at least one sensible member.

13. An apparatus as claimed in claim 12, wherein the at least one sensible member comprises a plurality of circumferentially spaced sensible members.

14. An apparatus as claimed in claim 13, wherein the sensor comprises first and second circumferentially spaced sensors.

15. An apparatus as claimed in claim 14, wherein the sensible members are sized and spaced such that a single sensible member may be circumferentially aligned with one of the first and second sensors, both of the first and second sensors, or none of the first and second sensors, depending upon the rotational orientation of the fluid cartridge relative to the percutaneous port.

16. An apparatus as claimed in claim 13, wherein the plurality of circumferentially spaced sensible members are separated by non-conductive regions.

17. An apparatus as claimed in claim 16, wherein the sensor comprises first and second circumferentially spaced sensors, each including a pair of electrical contacts.

18. An apparatus as claimed in claim 17, wherein

the sensible members are electrically conductive, and

the first and second circumferentially spaced sensors are respectively sized and spaced such that, depending upon the rotational orientation of the fluid cartridge relative to the percutaneous port, a single sensible member can contact both of the electrical contacts in one of the first and second sensors, can simultaneously contact both of the electrical contacts in both of the first and second sensors, and cannot simultaneously contact both of the electrical contacts in both of the first and second sensors.

19. An apparatus as claimed in claim 12, wherein the percutaneous port includes an exterior having a porous region configured to promote soft tissue ingrowth.

20. An apparatus as claimed in claim 12, further comprising:

a controller operably connected to the sensor and configured to perform a predefined operation in response to sensed rotational movement of the fluid cartridge relative to the percutaneous port.

21. An apparatus as claimed in claim 20, wherein

the fluid transfer device is configured to transfer fluid at a plurality of flow rates;

and

the predefined operation comprises increasing or decreasing the flow rate.

22. An apparatus as claimed in claim 12, wherein

the fluid cartridge housing defines an internal volume, and the substantially cylindrical side wall and the end wall abut portions of the percutaneous port;

and

the fluid cartridge includes a bladder located within the fluid cartridge housing that has an outer surface and an inner surface, the inner surface defining a fluid storage volume having a full state that is substantially equal to the internal volume of the housing.

23. An apparatus as claimed in claim 12, wherein

the fluid cartridge housing includes a fluid reservoir;

and

the at least one sensible member is located on the fluid cartridge housing in spaced relation to the needle.

24. An apparatus as claimed in claim 12, wherein the fluid transfer device includes a pump that receives fluid from the fluid cartridge by way of the percutaneous port and the pump is positioned relative to the percutaneous port such that the pump will be located subcutaneously when the percutaneous port is located percutaneously.

25. An apparatus as claimed in claim 12, wherein

the fluid cartridge housing defines an outer diameter and includes a fluid reservoir;

and

the percutaneous port defines an inner diameter that is substantially equal to the outer diameter of the fluid cartridge housing.

26. An apparatus, comprising:

a fluid cartridge including a housing with a substantially cylindrical side wall and an end wall, a needle extending from the housing end wall, and at least one sensible member mounted directly on the housing end wall; and

a partially implantable medical device including

means for percutaneously receiving the fluid cartridge housing such that the fluid cartridge can rotate about an axis defined by the needle,

an implantable operative portion including a pump, and

a sensor for sensing the at least one sensible member.

27. An apparatus as claimed in claim 26, wherein the at least one sensible member comprises a plurality of circumferentially spaced sensible members.

28. An apparatus as claimed in claim 27, wherein the sensor comprises first and second circumferentially spaced sensors.

29. An apparatus as claimed in claim 26, wherein the means for percutaneously receiving the fluid cartridge housing includes an exterior having a porous region configured to promote soft tissue ingrowth.

30. An apparatus as claimed in claim 26, wherein the pump is positioned relative to the means for percutaneously receiving the fluid cartridge housing such that the pump will be located subcutaneously when the means for percutaneously receiving the fluid cartridge housing is located percutaneously.

31. An apparatus as claimed in claim 26, wherein

the fluid cartridge housing defines an internal volume, and the substantially cylindrical side wall and the end wall abut portions of the means for percutaneously receiving the fluid cartridge housing;

and

the fluid cartridge includes a bladder located within the fluid cartridge housing that has an outer surface and an inner surface, the inner surface defining a fluid storage volume having a full state that is substantially equal to the internal volume of the housing.