Endolumenal sealant delivery apparatus and methods

• US 8,206,430 B2
• Filed: 04/21/2008
• Issued: 06/26/2012
• Est. Priority Date: 04/21/2008
• Status: Active Grant

• Current Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Original Assignee: Medtronic Vascular, Inc. (Medtronic Plc)
• Inventors: Mafi, Masoumeh, Bruszewski, Walter
• Primary Examiner(s): Tyson, Melanie
• Assistant Examiner(s): DANG, PHONG SON H
• Application Number:
  US12/106,421
• Publication Number:
  US 20090264821A1
• Time in Patent Office: 1,527 Days
• Field of Search: 623/1.11, 606/191, 604 9601-10314
• US Class Current: 623/1.11
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/821 Ostial stents
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2250/0062 Kits of prosthetic parts to be assembled in various combinations for forming different prostheses
• CPC Class Codes: A61F 2250/0069 Sealing means
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00

Abstract

Endolumenally sealing a zone around the puncture and dilation area of a stent-graft fenestration or sealing the juncture between two lumens with an expandable sealant delivery device. In exemplary embodiments, an expandable sealant delivery device includes a catheter mounted balloon, which has a microporous membrane or a plurality of pores suitable for delivering a surgical sealant.

Claims

1. Endolumenal sealant delivery apparatus for delivering sealant in a lumen of a human body comprising:

a catheter;

an expandable balloon having a region having a plurality of micropores adapted to allow surgical sealant to pass therethrough;

said expandable balloon being coupled to said catheter; and

a graft surrounding at least a portion of said expandable balloon, which has a region with a plurality of micropores, said graft having a region including a plurality of micropores aligned with said expandable balloon region having a plurality of micropores.

2. The apparatus of claim 1, further including an inner expandable balloon, said expandable balloon, which has a region with a plurality of micropores, surrounding at least a portion of said inner balloon to form a sealant chamber therebetween.

3. The apparatus of claim 2, wherein said inner balloon forms an inner chamber and said catheter includes a lumen fluidly coupled to said inner chamber for delivering fluid to said inner chamber to expand said inner expandable balloon, said catheter further including a sealant lumen fluidly coupled to the sealant chamber formed between said balloons.

4. The apparatus of claim 2, wherein said inner expandable balloon is formed from semi-compliant material and said expandable balloon that surrounds at least a portion of the inner balloon to form a sealant chamber therebetween is formed from compliant material.

5. The apparatus of claim 2, further including a central tube extending through said catheter and in within said inner expandable balloon, wherein each balloon has a distal end and a proximal end, said distal ends being coupled to said central tube and said proximal ends being coupled to said catheter.

6. The apparatus of claim 2, wherein said inner expandable balloon encapsulates said expandable balloon.

7. The apparatus of claim 2, wherein said pores have a diameter in a range of about 2microns to about 500 microns.

8. The apparatus of claim 1, further including first and second radiopaque markers, wherein said region, which has a plurality of micropores, has a distal end and a proximal end, said first radiopaque marker being positioned adjacent to said proximal end and said second radiopaque marker being positioned adjacent to said distal end.

9. The apparatus of claim 8, further including a central tube extending through said catheter and within said expandable balloon, said markers being coupled to said central tube.

10. The apparatus of claim 1 , wherein said region, which has a plurality of micropores, forms a 360 degree band.

11. The apparatus of claim 10, wherein said region, which has a plurality of micropores, is cylindrical.

12. Endolumenal sealant delivery apparatus for delivering sealant in a lumen of a human body comprising:

a catheter;

an expandable balloon having a region having a plurality of micropores adapted to allow surgical sealant to pass therethrough;

said expandable balloon being coupled to said catheter; and

a stent-graft surrounding at least a portion of said expandable balloon, which has a region with a plurality of micropores, the stent-graft having a region including a plurality of micropores aligned with said expandable balloon region having a plurality of micropores.

13. The apparatus of claim 12, further including an inner expandable balloon, said expandable balloon, which has a region with a plurality of micropores, surrounding at least a portion of said inner balloon to form a sealant chamber therebetween.

14. The apparatus of claim 13, wherein said inner balloon forms an inner chamber and said catheter includes a lumen fluidly coupled to said inner chamber for delivering fluid to said inner chamber to expand said inner expandable balloon, said catheter further including a sealant lumen fluidly coupled to the sealant chamber formed between said balloons.

15. The apparatus of claim 13, wherein said inner expandable balloon is formed from semi-compliant material and said expandable balloon that surrounds at least a portion of the inner balloon to form a sealant chamber therebetween is formed from compliant material.

16. The apparatus of claim 13, further including a central tube extending through said catheter and in within said inner expandable balloon, wherein each balloon has a distal end and a proximal end, said distal ends being coupled to said central tube and said proximal ends being coupled to said catheter.

17. The apparatus of claim 13, wherein said inner expandable balloon encapsulates said expandable balloon.

18. The apparatus of claim 13, wherein said pores have a diameter in a range of about 2microns to about 500 microns.

19. The apparatus of claim 12, further including first and second radiopaque markers, wherein said region, which has a plurality of micropores, has a distal end and a proximal end, said first radiopaque marker being positioned adjacent to said proximal end and said second radiopaque marker being positioned adjacent to said distal end.

20. The apparatus of claim 19, further including a central tube extending through said catheter and within said expandable balloon, said markers being coupled to said central tube.

21. The apparatus of claim 12, wherein said region, which has a plurality of micropores, forms a 360 degree band.

22. The apparatus of claim 21, wherein said region, which has a pura1ity of micropores, is cylindrical.