Analysis methods, analysis device waveform generation methods, analysis devices, and articles of manufacture

• US 8,212,206 B2
• Filed: 09/03/2004
• Issued: 07/03/2012
• Est. Priority Date: 09/04/2003
• Status: Active Grant

• Current Assignee: Flir Detection, Inc. (Teledyne Technologies Incorporated)
• Original Assignee: Griffin Analytical Technologies, LLC (Teledyne Technologies Incorporated)
• Inventors: Patterson, Garth E., Wells, James Mitchell, Rardin, Brent
• Primary Examiner(s): Vanore, David A
• Assistant Examiner(s): Smyth, Andrew
• Application Number:
  US10/570,707
• Publication Number:
  US 20070162232A1
• Time in Patent Office: 2,860 Days
• Field of Search: None
• US Class Current: 250/282
• CPC Class Codes: H01J 49/022 Circuit arrangements, e.g. for generating deviation currents or voltages regulating electric or magnetic variables in general, e.g. current, magnetic field G05F; Components associated with high voltage supply high voltage supply per se H02M
• CPC Class Codes: H01J 49/10 Ion sources; Ion guns
• CPC Class Codes: H01J 49/38 Omegatrons ; using ion cyclotron resonance

Abstract

In one implementation, an analysis device operational method includes providing a plurality of levels of programming abstraction corresponding to programming of an analysis device configured to analyze a sample, receiving input data corresponding to one of the levels of programming abstraction, processing the input data to generate analysis control data, and implementing an operation with respect to analysis of the sample using the analysis control data.

Claims

1. A method for carrying out mass spectroscopic analysis of a sample comprising the steps of:

a) providing a sample to be analyzed within a mass spectrometer;

b) querying a user via an interface device to select one of a plurality of processes for generating a voltage waveform to be utilized to control ions of the sample according to their mass-to-charge ratio, the querying step having a plurality of selectable choices including;

i. selecting a manual input of discrete data values defining a voltage waveform;

or

ii. selecting a manual input of an equation defining a function from which discrete data values are generated to define a voltage waveform;

c) receiving an input on the basis of the selection carried out in the querying step;

d) providing the received input to a data processing element which converts either the user input discrete data values or the discrete data values resulting from the user input equation to digital discrete data for driving a waveform generator;

e) generating a first set of digital discrete data;

f) converting the first set of digital discrete data to an analog signal using a conversion circuit;

g) generating a voltage waveform to be utilized to control the ions of the sample according to their mass-to-charge ratio; and

h) applying the generated voltage waveform to an electrode in the mass spectrometer to control motion of the ions of the sample.

2. The method of claim 1 further comprising the step of varying, during the application of the generated voltage waveform to the electrode, one or more characteristics of the voltage waveform selected from the group consisting of frequency, amplitude, and phase.

3. The method of claim 1 further comprising the step of storing the first set of digital discrete data on an addressed computer memory including a writing step for writing the first set of digital discrete data to a plurality of addressed locations of the addressed computer memory.

4. The method of claim 3 further comprising the step of outputting the first set of digital discrete data to the conversion circuit of step (f) using data regarding the addressed locations.

5. The method of claim 4 further comprising the step of generating a second set of digital discrete data.

6. The method of claim 5 further comprising the step of storing the second set of digital discrete data on the addressed computer memory including a writing step for writing the second set of digital discrete data to a plurality of additional addressed locations of the addressed computer memory.

7. The method of claim 6 further comprising the step of outputting the second set of digital discrete data to the conversion circuit of step (f) using data regarding the additional addressed locations.

8. The method of claim 7 further comprising repeating steps (f) through (g) using the second set of digital discrete data.

9. The method of claim 8 further comprising the step of conducting the outputting step of the first and second sets of discrete digital data in parallel.

10. The method of claim 4 where the outputting step is carried out at a substantially constant rate.

11. The method of claim 7 where the outputting step is carried out at a substantially constant rate.

12. The method of claim 9 where the outputting step is carried out at a substantially constant rate.