Nerve cuff, method and apparatus for manufacturing same

• US 8,214,056 B2
• Filed: 06/04/2007
• Issued: 07/03/2012
• Est. Priority Date: 06/02/2006
• Status: Expired due to Fees

• Current Assignee: 4491343 Canada Inc.
• Original Assignee: Neurostream Technologies General Partnership
• Inventors: Imbeau, Marc-Olivier, Vallieres, Jean-Martin, Hoffer, Joaquin Andres
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Stice, Paula J
• Application Number:
  US11/809,934
• Publication Number:
  US 20080065184A1
• Time in Patent Office: 1,856 Days
• Field of Search: None
• US Class Current: 607/118
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: B29C 39/10 incorporating preformed parts or layers, e.g. casting around inserts or for coating articles coating a surface by casting in general B05D1/30, B29C39/126 takes precedence
• CPC Class Codes: B29C 45/14426 Coating the end of wire-like or rod-like or cable-like or blade-like or belt-like articles
• CPC Class Codes: Y10T 29/49117 Conductor or circuit manufacturing

Abstract

A nerve cuff comprising a wall band member having an inner surface defining a lumen when the wall band member is in a closed configuration for receiving a nerve therethrough. At least one longitudinal and contiguous conductor extends within the lumen. The conductor is insulated and has at least one exposed portion thereby providing an electrode. When mounting the nerve cuff to a nerve, each electrode is in electrical communication with the nerve. A multi-channel nerve cuff further comprises a plurality of longitudinal ridges formed on the inner surface with each adjacent pair of ridges defining a longitudinal chamber. Each chamber comprises a respective conductor extending therein. When mounting the multi-channel nerve cuff to the nerve, the ridges abut the nerve providing for each chamber to isolate respective longitudinal portions of the nerve. A method and an apparatus for manufacturing such nerve cuffs are also disclosed.

Claims

1. A nerve cuff comprising:

a wall band member having proximal and distal ends thereof, an inner surface defining a lumen extending between the proximal end and the distal end when said wall band member is in a closed configuration for receiving a nerve therethrough; and

at least one pair of contiguous conductors extending along the inner surface between the proximal end and the distal end, wherein each conductor of the at least one pair of contiguous conductors comprises at least one exposed portion situated between the proximal end and the distal end and wherein the remaining portion of each conductor of the at least one pair of contiguous conductors is insulated, thereby providing at least two electrodes,

wherein, when mounting said nerve cuff to a nerve, said electrodes are in electrical communication with the nerve.

2. The nerve cuff according to claim 1, further comprising at least two ridges formed on said inner surface and extending between the proximal end and the distal end, wherein a pair of the at least one pair of contiguous conductors is situated between each adjacent pair of ridges, wherein each adjacent pair of ridges and each portion of the inner surface situated between the adjacent pair of ridges defines a chamber, wherein, when mounting said nerve cuff to the nerve, said ridges abut the nerve providing for each said chamber to isolate respective portions of the nerve situated between each adjacent pair of ridges.

3. The nerve cuff according to claim 2, wherein said inner surface comprises a plurality of protuberances extending between the proximal end and the distal end, each of the plurality of protuberances situated between one of the adjacent pairs of ridges and having at least one pair of contiguous conductors mounted thereto.

4. The nerve cuff according to claim 2, further comprising a ground wire embedded within said ridges.

5. The nerve cuff according to claim 3, wherein said protuberance provides for positioning each electrode at substantially the same level as said ridges relative to said inner surface.

6. The nerve cuff according to claim 3, wherein each pair of contiguous conductors is embedded within a respective said protuberance.

7. The nerve cuff according to claim 3, wherein each said protuberance is apertured so as to expose each exposed portion of each said conductor thereby providing each said electrode.

8. The nerve cuff according to claim 3, wherein each said pair of contiguous conductors is mounted on a respective said protuberance.

9. The nerve cuff according to claim 8, wherein each said pair of contiguous conductors is mounted along substantially a full length of said protuberance.

10. The nerve cuff according to claim 1, wherein each said conductor is embedded within said inner surface, said inner surface being apertured so as to expose each exposed portion of each said conductor thereby providing each said electrode.

11. The nerve cuff according to claim 1, wherein each said conductor is mounted on said inner surface.

12. The nerve cuff according to claim 1, wherein said inner surface further comprises at least one protuberance extending along the inner surface between the proximal end and the distal end, wherein at least one pair of contiguous conductors is mounted to said protuberance.

13. The nerve cuff according to claim 12, wherein each pair of contiguous conductors is embedded within each protuberance.

14. The nerve cuff according to claim 13, wherein said protuberance is apertured so as to expose each exposed portion of each said conductor of the at least one pair of contiguous conductors, thereby providing each said electrode.

15. The nerve cuff according to claim 12, wherein the at least one pair of contiguous conductors is mounted on said protuberance.

16. The nerve cuff according to claim 12, wherein a said protuberance is so configured as to provide for each electrode to be in contact with or at least near a surface of the nerve when said nerve cuff is mounted thereto.

17. The nerve cuff according to claim 1, wherein each pair of contiguous conductors comprises a pair of wires.

18. The nerve cuff according to claim 17, wherein said pair of wires are insulated, said insulation being removed at said at least one exposed portion situated between the proximal end and the distal end providing said electrode.

19. The nerve cuff according to claim 1, wherein an end of each conductor protrudes beyond the proximal end or the distal end.

20. The nerve cuff according to claim 19, wherein said end is capped with an insulating material.

21. The nerve cuff according to claim 1, further comprising a ground wire mounted to said inner surface.

22. The nerve cuff according to claim 21, wherein said ground wire is embedded within said inner surface.

23. The nerve cuff according to claim 1, wherein said wall band member further comprises a closure for maintaining said wall band member in said closed configuration.

24. The nerve cuff according to claim 23, wherein said closure comprises mutually interdigitating members positioned at each lateral side of said wall band member.

25. The nerve cuff according to claim 24, wherein said interdigitating members are combined with a sealing tube.

26. The nerve cuff according to claim 24, wherein a rod-like member is inserted through said mutually interdigitating members when interdigitated thereby closing said interdigitated members together.

27. The nerve cuff according to claim 1, wherein said wall band member further comprises one or more ports for connection to an agent delivery system.

28. A nerve cuff comprising:

a wall band member having proximal and distal ends thereof, an inner surface defining a lumen extending between the proximal end and the distal end when said wall band member is in a closed configuration for receiving a nerve therethrough;

at least one protuberance extending along the inner surface between the proximal end and the distal end; and

at least one pair of contiguous conductors mounted to each said protuberance and extending along substantially a full length of the protuberance, wherein each conductor comprises at least one exposed portion situated between the proximal end and the distal end and an insulated remaining portion, and wherein each pair of contiguous conductors provides at least two electrodes;

wherein, when mounting said nerve cuff to a nerve, said at least one protuberance provides for said electrodes to be in contact with or at least near the surface of the nerve.

29. The nerve cuff according to claim 28, further comprising a plurality of ridges formed on said inner surface and extending between the proximal end and the distal end, wherein each pair of contiguous conductors mounted to each protuberance is situated between each adjacent pair of ridges, each adjacent pair of ridges and each portion of the inner surface situated between the adjacent pair of ridges defines a chamber, and wherein, when mounting said nerve cuff to the nerve, said ridges abut the nerve providing for each said chamber to isolate respective portions of the nerve situated between each pair of ridges.

30. The nerve cuff according to claim 29, wherein each protuberance provides for positioning each electrode at substantially the same level as said ridges relative to said inner surface.

31. The nerve cuff according to claim 30, wherein each pair of contiguous conductors comprises a pair of wires.

32. The nerve cuff according to claim 30, wherein each pair of contiguous conductors comprises an end protruding beyond the proximal end or the distal end, said protruding end being capped with an insulating material.

33. The nerve cuff according to claim 28, further comprising a ground wire mounted to said wall band member.

34. The nerve cuff according to claim 28, wherein said wall band member further comprises a closure.

35. The nerve cuff according to claim 28, wherein said wall band member further comprises ports for connection to an agent delivery system.

36. A nerve cuff comprising:

a wall band member having proximal and distal ends thereof, an inner surface defining a lumen extending between the proximal end and the distal end when said wall band member is in a closed configuration for receiving a nerve therethrough;

a plurality of longitudinal ridges formed on said inner surface and extending between the proximal end and the distal end, each adjacent pair of said ridges defining a chamber;

at least one protuberance extending between the proximal end and the distal end, each protuberance situated between each adjacent pair of ridges; and

at least one and pair of contiguous conductors mounted along essentially a full length of the protuberance, each conductor being insulated and having at least one exposed portion situated between the proximal end and the distal end thereby providing at least one electrode,

wherein, when mounting said nerve cuff to the nerve, said ridges abut the nerve providing for each said chamber to isolate respective portions of the nerve situated between each adjacent pair of ridges, each said protuberance providing for each electrode to be in contact with or at least near the surface of the nerve.