Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration

  • US 8,216,138 B1
  • Filed: 10/23/2008
  • Issued: 07/10/2012
  • Est. Priority Date: 10/23/2007
  • Status: Expired due to Fees
First Claim
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1. A method, comprising:

  • obtaining, using one or more processors, an analyte related signal from an analyte sensor with at least a portion in fluid contact with an interstitial fluid;

    obtaining, using the one or more processors, a reference signal from a reference sensor in contact with a blood sample from an off-finger sample acquisition site;

    correlating, using the one or more processors, the analyte related signal with the reference signal;

    comparing, using the one or more processors, the analyte related signal to the reference signal;

    confirming, using the one or more processors, the deviation between the analyte related signal and the reference signal does not exceed a predetermined threshold; and

    outputting, using the one or more processors, the analyte related signal;

    wherein the predetermined threshold includes a lag time of approximately two minutes between the analyte related signal and the reference signal.

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