Method for treatment of inflammation

  • US 8,216,599 B2
  • Filed: 02/13/2003
  • Issued: 07/10/2012
  • Est. Priority Date: 02/13/2002
  • Status: Expired due to Fees
First Claim
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1. A method of treating a subject having an inflammatory condition characterized by a detectable clinical symptom or change in a level of a biochemical marker with respect to the normal range of the marker, the method comprising:

  • administering to the subject a dose corresponding to between about 0.1 mg/kg body weight and 2000 mg/kg body weight daily of a first treatment agent comprised of an olive plant extract having a weight ratio of hydroxytyrosol to oleuropein of between about 1;

    1 and about 200;

    1; and

    continuing said administration until there is observed a return of the marker level to the normal range or a desired change in the clinical symptom,where the marker or the clinical symptom is selected from the group consisting of(i) elevated levels of C-reactive protein in the case of coronary inflammation;

    (ii) respiratory distress in the case of bronchial inflammation; and

    (iii) elevated CSF levels of isoprostanes or clinical symptoms determined from neuropsychological testing in the case of neuro inflammation.

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