Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders

CAFC
  • US 8,227,484 B2
  • Filed: 03/08/2012
  • Issued: 07/24/2012
  • Est. Priority Date: 07/17/2002
  • Status: Active Grant
First Claim
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1. A method for treating pseudobulbar affect or emotional lability, the method comprising administering to a patient in need thereof dextromethorphan in combination with quinidine, wherein the amount of dextromethorphan administered comprises from about 20 mg/day to about 60 mg/day and wherein the amount of quinidine administered comprises from about 10 mg/day to about 30 mg/day with the proviso that the weight-to-weight ratio of dextromethorphan to quinidine is 1:

  • 0.75 or less of quinidine.

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