Wearable monitoring system

• US 8,233,969 B2
• Filed: 06/28/2007
• Issued: 07/31/2012
• Est. Priority Date: 07/05/2006
• Status: Expired due to Fees

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.), Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Inventors: Muhlsteff, Jens, Thijs, Jeroen Adrianus Johannes
• Primary Examiner(s): Patel, Niketa
• Assistant Examiner(s): FAIRCHILD, MALLIKA DIPAYAN
• Application Number:
  US12/306,000
• Publication Number:
  US 20090204013A1
• Time in Patent Office: 1,860 Days
• Field of Search: 600/388, 600/509, 600/513
• US Class Current: 600/509
• CPC Class Codes: A41B 9/001 Underpants or briefs specially adapted for men A41B9/02; specially adapted for ladies A41B9/04
• CPC Class Codes: A41D 13/1281 with incorporated means for medical monitoring
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/0535 Impedance plethysmography for measuring blood flow A61B5/0295
• CPC Class Codes: A61B 5/6804 Garments; Clothes

Abstract

A system for measuring/monitoring the vital signs of a patient especially blood pressure, comprising a plurality of electrodes arranged at least in the waistband of an undergarment, and means for deriving measurements from the electrodes using pulse-transit times.

Claims

1. A measuring system for measuring blood pressure of a patient, comprising:

underpants having a waistband, a right leg portion, and a left leg portion;

a plurality of electrodes carried by the underpants, the plurality of electrodes including one or more electrode pairs carried by the waistband, one or more electrode pairs carried by the right leg portion, and one or more electrode pairs carried by the left leg portion;

a power supply that supplies power to the measuring system, wherein the power supply is configured to inject currents into the electrode pairs; and

a signal processing circuit configured to receive output signals generated by the plurality of electrodes carried by the underpants to determine pulse-transit times based on the output signals received from the plurality of electrodes, wherein the output signals are indicative of voltage changes across the electrode pairs caused by the injected currents, and wherein the signal processing circuit is further configured to determine the blood pressure of the patient based on the pulse-transit times.

2. The measuring system of claim 1, wherein individual electrodes of the plurality of electrodes comprise dry electrodes of conductive rubber.

3. The measuring system of claim 1, wherein the electrodes carried by the right leg portion enable measurements of the right femoralis, wherein electrodes carried by the left leg portion enable measurements of the left femoralis, wherein the signal processing circuit determines pulse-transit times using:

an ECG measurement based on the one or more electrode pairs carried by the waistband of the underpants; and

an impedance plethysmography measurement based on the one or more electrode pairs carried by the right leg portion or the one or more electrode pairs carried by the left leg portion;

and wherein the signal processing circuit is configured to determine pulse-transit times based on both the ECG measurement and the impedance plethysmography measurement.

4. The measuring system of claim 1, wherein the signal processing circuit is further configured to determine electrical activity of a heart of the patient based on measurements derived from the one or more electrode pairs carried by the waistband of the underpants.

5. The measuring system of claim 1, wherein the blood pressure is determined by applying the pulse-transit times in accordance with a Moens-Korteweg equation, wherein the pulse-transit times correspond to pulse wave velocity, and wherein the Moens-Korteweg equation equates pulse wave velocity c to the square root of the ratio of the product of artery wall thickness h and tangential elasticity E with the product of twice the density ρ

and artery radius R, as follows;

c=√

((h·

E)/(2·

ρ

·

R)).

6. The measuring system of claim 3,

wherein the plurality of electrodes include at least four electrodes carried by the waistband, two electrodes carried by the right leg portion, and two electrodes carried by the left leg portion, wherein a first current is injected by the power supply into a first pair of electrodes, the first pair of electrodes comprising:

a first electrode of the electrodes carried by the waistband of the underpants, and

a first electrode of the electrodes carried by the right leg portion;

wherein a second current is injected by the power supply into a second pair of electrodes, the second pair of electrodes comprising;

a second electrode of the electrodes carried by the waistband of the underpants, and

a first electrode of the electrodes carried by the left leg portion;

wherein a first voltage change caused by the first current is measured across a third pair of electrodes to produce the impedance plethysmography measurement, the third pair of electrodes comprising;

a third electrode of the electrodes carried by the waistband of the underpants, and

a second electrode of the electrodes carried by the right leg portion;

wherein a second voltage change caused by the second current is measured across a fourth pair of electrodes to produce a second impedance plethysmography measurement, the fourth pair of electrodes comprising;

a fourth electrode of the electrodes carried by the waistband of the underpants, and

a second electrode of the electrodes carried by the left leg portion; and

wherein the pulse-transit times are based on both the ECG measurement and one or both of the impedance plethysmography measurement and/or the second impedance plethysmography measurement.

7. The measuring system of claim 1, further comprising a 3-axis accelerometer whereby the system can detect the patient'"'"'s posture or movements and compensate for signal artifacts caused by the patient'"'"'s posture or movements.

8. The measuring system according to claim 1, wherein the signal processing circuit includes a front-end circuit for receiving sensor signals means for storing data, and rf-transceiver for communication with an external system.

9. The measuring system of claim 8, wherein the signal processing circuit is further configured to receive manual input from the patient and to transmit information, relating to the condition of the system and the condition of the patient, to the external system.

10. The measuring system of claim 9, further comprising an alarm for alerting the patient to a critical condition pertaining to the determined blood pressure of the patient.

11. The measuring system of claim 10, wherein the transmitted information with the external system includes an alert to a source of external professional assistance.

12. The measuring system of claim 8, wherein the system is arranged to operate as a Holter monitor or ambulatory electrocardiography device, so as to record cardiac activity over an extended period of time.

13. A system for measuring blood pressure of a patient, comprising:

underpants having a waistband and a leg portion;

a power supply to supply power for the system, wherein the power supply is configured to inject currents into electrode pairs, and wherein the power supply supplies power to perform measurements of voltage changes across electrode pairs caused by the injected currents;

a plurality of electrodes carried by the underpants, the plurality of electrodes including at least two electrode pairs carried by the waistband and at least two electrodes carried by the leg portion; and

a signal processing circuit configured to;

perform an ECG measurement using a first current injected by the power supply into a first electrode pair that is carried by the waistband of the underpants, wherein output signals indicative of voltage changes caused by the first injected current are generated by a second electrode pair that is carried by the waistband of the underpants;

perform a first impedance plethysmography measurement, wherein a second current is injected by the power supply into an electrode pair that is carried by the waistband of the underpants, wherein voltage changes caused by the injected second current are measured between an electrode pair that is carried by the waistband of the underpants;

perform a second impedance plethysmography measurement, wherein a third current injected by the power supply into an electrode pair having at least one electrode that is carried by the leg portion, wherein voltage changes caused by the injected third current are measured between an electrode pair having at least one electrode that is carried by the leg portion;

determine a first pulse-transit time based on the ECG measurement and the first impedance plethysmography measurement;

determine a second pulse-transit time based on the ECG measurement and the second impedance plethysmography measurement; and

determine the blood pressure of the patient based on the first pulse-transit time and the second pulse-transit time.

14. A system for measuring blood pressure of a patient, comprising:

underpants having a waistband and a leg portion;

a power supply to supply power for the system, wherein the power supply is configured to inject currents into electrode pairs, and wherein the power supply supplies power to perform measurements of voltage changes across electrode pairs caused by the injected currents;

a plurality of electrodes carried by the underpants, the plurality of electrodes including at least two electrode pairs carried by the waistband and at least two electrodes carried by the leg portion; and

a signal processing circuit configured to;

perform an ECG measurement using a first current injected by the power supply into a first electrode pair that is carried by the waistband of the underpants, wherein output signals indicative of voltage changes caused by the first injected current are generated by a second electrode pair that is carried by the waistband of the underpants;

perform an impedance plethysmography measurement, wherein a second current injected by the power supply into an electrode pair having at least one electrode that is carried by the leg portion, wherein voltage changes caused by the injected second current are measured between an electrode pair having at least one electrode that is carried by the leg portion;

determine a pulse-transit time based on the ECG measurement and the impedance plethysmography measurement; and

determine the blood pressure of the patient based on the pulse-transit time.