Oxygen enhancing membrane systems for implantable devices

  • US 8,255,032 B2
  • Filed: 01/15/2010
  • Issued: 08/28/2012
  • Est. Priority Date: 07/25/2003
  • Status: Active Grant
First Claim
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1. An implantable device for continuous in vivo measurement of an analyte concentration in a host, the implantable device comprising:

  • a sensing region operatively connected to electronic circuitry configured to generate a signal associated with a concentration of an analyte in a host; and

    a membrane located over the sensing region, wherein the membrane comprises a first domain comprising an enzyme configured to react with the analyte and a second domain configured to control a flux of the analyte and oxygen therethrough to the underlying first domain, wherein the first domain comprises a first silicone-containing polymer and the second domain comprises a second silicone-containing polymer, and wherein the second domain comprises a blend that comprises the second silicone-containing polymer and a hydrophilic polymer.

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