Devices and systems for the prevention of sudden infant death syndrome (SIDS)

• US 8,257,268 B2
• Filed: 07/15/2008
• Issued: 09/04/2012
• Est. Priority Date: 07/17/2007
• Status: Active Grant

• Current Assignee: Ainslie Macleod, Daniel David Rubens
• Original Assignee: Ainslie Macleod, Daniel David Rubens
• Inventors: MacLeod, Ainslie, Rubens, Daniel David
• Primary Examiner(s): DUNSTON, JENNIFER ANN
• Application Number:
  US12/173,144
• Publication Number:
  US 20090024043A1
• Time in Patent Office: 1,512 Days
• Field of Search: None
• US Class Current: 600/484
• CPC Class Codes: A61B 17/135 inflatable for measuring blood pressure A61B5/022; inflatable pressure pads A61F5/34
• CPC Class Codes: A61B 17/42 Gynaecological or obstetrical instruments or methods ligaturing clamps or clips for the umbilical cord A61B17/122; curettage A61B17/320708; dilators A61M29/00
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61F 2007/0233 connected to or incorporated in clothing or garments A61F2007/023 takes precedence
• CPC Class Codes: A61F 7/02 Compresses or poultices for effecting heating or cooling
• CPC Class Codes: A61F 7/10 Cooling bags, e.g. ice-bags
• CPC Class Codes: A61M 1/3639 Blood pressure control, pressure transducers specially adapted therefor
• CPC Class Codes: A61M 16/0666 Nasal cannulas or tubing devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02
• CPC Class Codes: A61M 16/0672 Nasal cannula assemblies for oxygen therapy
• CPC Class Codes: A61M 2205/3606 cooled
• CPC Class Codes: A61M 2230/06 Heartbeat rate only
• CPC Class Codes: A61M 2230/202 partial carbon oxide pressure, e.g. partial dioxide pressure (P-CO2)
• CPC Class Codes: A61M 2240/00 Specially adapted for neonatal use

Abstract

Methods and systems for preventing the underlying anatomical cause that gives rise to a predisposition to SIDS are provided. Methods and systems are provided for the diagnosis of infants predisposed to SIDS. Methods and systems are provided for the therapeutic treatment of infants predisposed to SIDS. A treatment device includes an auditory stimulation system, a monitoring system, a warming system and a response system that can respond to and alleviate crisis situations.

Claims

1. A treatment system for treating an infant previously diagnosed as predisposed to Sudden Infant Death Syndrome (SIDS), the infant having a brainstem adjacent a back of a neck, comprising:

a) an auditory stimulation system that reproduces a specific melodic and harmonic arrangement of tones in a mixolydian mode through at least one sound transducer to stimulate the auditory system of the infant;

b) a monitoring system including,

i) a heart rate monitor that monitors a heart rate of the infant, and

ii) a first CO₂ monitor that measures a blood CO₂ of the infant;

c) a warming system that maintains a body of the infant at a substantially constant core temperature; and

d) a response system activated when the monitoring system indicates that there is a decrease in the heart rate and an increase in the blood CO₂ associated with activation of a diving reflex, the response system including,

i) an oxygen delivery system to deliver inhalable oxygen to the infant,

ii) an epinephrine delivery system to deliver inhalable epinephrine to the infant, and

iii) a cooling system to cool a portion of the infant,

wherein the warming system and the cooling system are integrated within a common suit for the infant, and a portion of the cooling system within the suit is located for placement at the back of the neck of the infant to sufficiently cool the brainstem of the infant to interrupt the diving reflex and to initiate a gasp reflex and thereby increase a partial pressure of oxygen in the blood of the infant.

2. A treatment system according to claim 1, wherein:

said at least one sound transducer of said auditory system includes a pair of earphones that are couplable directly to the ears of the infant.

3. A treatment system according to claim 1, wherein:

said auditory stimulation system is automatically activated to reproduce said tones upon signal from said monitoring system.

4. A treatment system according to claim 1, wherein:

said monitoring system further includes a second CO₂ monitor that measures environmental CO₂ proximate the infant.

5. A treatment system according to claim 1, wherein:

said monitoring system further includes a respiration rate monitor that identifies increased respiration of the infant, said response system activated by an increase in respiration rate to above a predetermined level.

6. A treatment system according to claim 1, wherein:

said monitoring system further includes a core temperature monitor to measure the core temperature of the infant,

a peripheral temperature monitor to measure the peripheral temperature of the infant, such that the core and peripheral temperatures can be compared relative to each other, and

a cerebral oximeter to detect a drop in brain oximetry in the infant.

7. A treatment system according to claim 1, wherein:

said warming system includes an enclosure through which a warming fluid is circulated.

8. A treatment system according to claim 1, wherein:

said cooling system provides sufficient cooling to the brainstem to cause the brainstem to interpret that the partial pressure of oxygen in the blood is lower than it actually is.

9. A treatment system for treating an infant previously diagnosed as predisposed to Sudden Infant Death Syndrome (SIDS), the infant having a brainstem adjacent at back of a neck, comprising:

a) a monitoring system including,

i) a heart rate monitor that monitors a heart rate of the infant, and

ii) a first CO₂ monitor that measures a blood CO₂ of the infant, and

iii) a cerebral oximeter to detect a drop in brain oximetry in the infant; and

b) a warming system that maintains a body of the infant at a substantially constant core temperature; and

c) a response system activated when the monitoring system indicates that there is a decrease in the heart rate and an increase in the blood CO₂ and decrease in brain oximetry associated with activation of a diving reflex, the response system including,

i) an oxygen delivery system to deliver inhalable oxygen to the infant, and

ii) a cooling system to cool a portion of the infant,

wherein the warming system and the cooling system are integrated within a common suit for the infant, and a portion of the cooling system within the suit is located for placement at the back of the neck of the infant to cool the brainstem of the infant to interrupt the diving reflex and to initiate a gasp reflex and thereby increase a partial pressure of oxygen in the blood of the infant.

10. A treatment system according to claim 9, wherein:

said monitoring system further includes a second CO₂ monitor that measures environmental CO₂ proximate the infant.

11. A treatment system according to claim 9, wherein:

said monitoring system further includes a respiration rate monitor that identifies increased respiration of the infant, said response system activated by an increase in respiration rate to above a predetermined level.

12. A treatment system according to claim 9, wherein:

said monitoring system further includes a core temperature monitor to measure the core temperature of the infant, and

a peripheral temperature monitor to measure the peripheral temperature of the infant, such that the core and peripheral temperatures can be compared relative to each other.

13. A treatment system according to claim 9, wherein:

said response system includes an epinephrine delivery system to deliver inhalable epinephrine to the infant.

14. A treatment system according to claim 9, wherein:

said cooling system provides sufficient cooling to the brainstem to cause the brainstem to interpret that the partial pressure of oxygen in the blood is lower than it actually is.

15. A stimulation system for an infant predisposed to Sudden Infant Death Syndrome (SIDS), the infant having an auditory system, and the stimulation system for use with a monitoring system including a heart rate monitor and a temperature sensor, comprising:

an auditory stimulation system including an earphone having at least one sound transducer and the temperature sensor of the monitoring system integrated into the earphone for placement within an ear canal of the infant, the auditory system, when activated, produces a melodic and harmonic arrangement of tones in a mixolydian mode and outside the range of 2000-4000 Hz and outside the range of 5000-8000 Hz, said tone emitted through the at least one sound transducer to stimulate the auditory system of the infant, said auditory stimulation system including an input to receive a signal from the heart rate monitor such that when said auditory stimulation system receives a signal from the heart rate monitor indicating that the infant heart rate has reached a predetermined rate, the auditory stimulation system is automatically activated.

16. A stimulation system according to claim 15, wherein:

said tones are accompanied by a percussive beat of 50-60 beats per minute.