Display of modeled magnetic fields

• US 8,265,910 B2
• Filed: 10/09/2008
• Issued: 09/11/2012
• Est. Priority Date: 10/09/2007
• Status: Active Grant

• Current Assignee: Brainsway, Ltd.
• Original Assignee: Cervel Neurotech, Inc.
• Inventors: Mishelevich, David J., Schneider, M. Bret
• Primary Examiner(s): PATEL, SHAMBHAVI K
• Application Number:
  US12/679,960
• Publication Number:
  US 20110004450A1
• Time in Patent Office: 1,433 Days
• Field of Search: 703 1- 6, 600 9- 11, 600 13- 15, 600/544, 600/545
• US Class Current: 703/2
• CPC Class Codes: A61N 2/006 for magnetic stimulation of nerve tissue
• CPC Class Codes: A61N 2/02 using magnetic fields produced by coils, including single turn loops or electromagnets A61N2/12 takes precedence

Abstract

Methods and systems for modeling and displaying magnetic field intensities during Transcranial Magnetic Stimulation (TMS) are described, particularly methods and system for modeling and displaying TMS using overlapping magnetic fields to stimulate deep brain regions.

Claims

1. A method of generating a Transcranial Magnetic Stimulation (TMS) treatment plan for a patient, the method comprising the steps of:

displaying representations of a plurality of TMS electromagnets around a model of the patient'"'"'s brain;

calculating the intensity of the magnetic field for a plurality of brain regions including a deep brain target based on the positions of the TMS electromagnets relative to the brain and based on pre-computed magnetic field models for each of the plurality of TMS electromagnets;

displaying the magnetic field intensity at the deep brain target on the model of the patient'"'"'s brain and on non-target regions in the patient'"'"'s brain; and

moving the representation of at least one TMS electromagnet and re-calculating the intensity of the magnetic field for the deep brain target until the magnetic field intensity at the deep brain target is above a stimulation threshold while the magnetic field intensity at non-target regions is below a stimulation threshold.

2. The method of claim 1, further comprising displaying a model of the patient'"'"'s brain and determining a deep brain target on the model of the patient'"'"'s brain.

3. The method of claim 1, further comprising pre-computing the magnetic field model for each of the TMS electromagnets.

4. The method of claim 1, further comprising registering the position of the representations of the TMS electromagnets relative to the model of the patient'"'"'s head with the position of actual TMS electromagnets relative to the patient'"'"'s head.

5. The method of claim 1, wherein the step of calculating the intensity of the magnetic field for each of a plurality of brain regions comprises linearly summing the overlapping magnetic field intensities for each brain region.

6. A method of generating a Transcranial Magnetic Stimulation (TMS) treatment plan for a patient, the method comprising the steps of:

displaying representations of a plurality of TMS electromagnets around a model of the patient'"'"'s brain;

calculating the intensity of the magnetic field for a deep brain target based on the positions of the TMS electromagnets relative to the brain and based on pre-computed magnetic field models for each of the plurality of TMS electromagnets;

displaying the magnetic field intensity at the deep brain target on the model of the patient'"'"'s brain; and

repositioning the representation of at least one TMS electromagnet and re-calculating the intensity of the magnetic field for the deep brain target until the magnetic field intensity at the deep brain target is above a stimulation threshold while the magnetic field intensity at non-target regions is below a stimulation threshold.

7. The method of claim 6, further comprising displaying a model of the patient'"'"'s brain and determining a deep brain target on the model of the patient'"'"'s brain.

8. The method of claim 6, further comprising pre-computing the magnetic field model for each of the TMS electromagnets.

9. The method of claim 6, further comprising registering the position of the representations of the TMS electromagnets relative to the model of the patient'"'"'s head with the position of actual TMS electromagnets relative to the patient'"'"'s head.

10. The method of claim 6, wherein calculating the intensity of the magnetic field for each of a plurality of brain regions comprises linearly summing the overlapping magnetic field intensities for each brain region.

11. A method of generating a Transcranial Magnetic Stimulation (TMS) treatment plan for a patient, the method comprising the steps of:

modeling representations of a plurality of TMS electromagnets around a model of the patient'"'"'s brain;

calculating the intensity of the magnetic field for a deep brain target based on the positions of the TMS electromagnets relative to the brain and based on pre-computed magnetic field models for each of the plurality of TMS electromagnets;

displaying the magnetic field intensity at the deep brain target on the model of the patient'"'"'s brain; and

repositioning the representation of at least one TMS electromagnet and re-calculating the intensity of the magnetic field for the deep brain target until the magnetic field intensity at the deep brain target is above a stimulation threshold while the magnetic field intensity at non-target regions is below a stimulation threshold.