Systems and methods for deriving relative physiologic measurements using a backend computing system

• US 8,271,093 B2
• Filed: 09/17/2004
• Issued: 09/18/2012
• Est. Priority Date: 09/17/2004
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Von Arx, Jeffrey A., Mazar, Scott T., Chavan, Abhi
• Primary Examiner(s): Patel, Niketa
• Assistant Examiner(s): ALTER, ALYSSA MARGO
• Application Number:
  US10/943,627
• Publication Number:
  US 20060064143A1
• Time in Patent Office: 2,923 Days
• Field of Search: 607/60
• US Class Current: 607/60
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/30 Blood pressure A61M2230/04 takes precedence
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: A61N 1/37217 characterised by the communication link, e.g. acoustic or tactile
• CPC Class Codes: A61N 1/37223 Circuits for electromagnetic coupling
• CPC Class Codes: A61N 1/37252 Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data

Abstract

One embodiment of the present invention relates to a system for deriving physiologic measurement values that are relative to ambient conditions. In one embodiment, the system comprises an implantable medical device (“IMD”), an external computing device, and a backend computing system. The IMD determines an absolute physiologic parameter value within a patient'"'"'s body, and communicates the absolute physiologic parameter value outside the patient'"'"'s body, for example, to the external computing device. Further, the external computing device receives the absolute physiologic parameter from the IMD and communicates it to the backend computing system. The backend computing system receives the absolute physiologic parameter value and obtains an ambient condition value outside the body that can affect the absolute physiologic parameter value. The backend computing system then calculates a relative physiologic parameter value from the ambient condition value and the absolute physiologic parameter value, and in some embodiments, stores the relative physiologic parameter value in a storage location, such as a memory or database.

Claims

1. A system for deriving relative physiologic measurement values, comprising:

an implantable medical device (“

IMD”

) operable to determine an absolute physiologic parameter value within a patient'"'"'s body and communicate the absolute physiologic parameter value outside the patient'"'"'s body, the IMD including a main body and a remote sensor system adapted to be implanted in the patient'"'"'s body, the main body including a receiver in acoustic communication with the remote sensor system, the remote sensor system operable to measure an absolute physiologic parameter value within the patient'"'"'s body and including a transmitter adapted to acoustically communicate the absolute physiologic parameter value to the receiver;

an external computing device including communication circuitry configured to wirelessly receive the absolute physiologic parameter value and an integral sensor configured to sense an ambient condition value outside the patient'"'"'s body, the external computing device comprising a single device operable to both;

wirelessly receive the absolute physiologic parameter value from the IMD; and

sense an ambient condition value outside the patient'"'"'s body related to the absolute physiologic parameter value;

the external computing device or a backend computing system operable to;

calculate a relative physiologic parameter value from the ambient condition value and the absolute physiologic parameter value; and

store the calculated relative physiologic parameter value.

2. The system as recited in claim 1, wherein the external computing device is operable to communicate the relative physiologic parameter value to the IMD, and wherein the IMD is further operable to receive the relative physiologic parameter value and store it in a memory.

3. The system as recited in claim 2, wherein the IMD is operable to provide therapy to a patient, and wherein the IMD uses the relative physiologic parameter value to determine the proper therapy to provide to the patient.

4. The system as recited in claim 3, wherein the therapy is selected from the group consisting of cardiac pacing therapy, anti-tachycardia therapy, drug delivery therapy, neurostimulation therapy, and blood pump therapy.

5. The system as recited in claim 2, wherein:

the IMD comprises a processor operable to generate patient therapy information based at least in part on the relative physiologic parameter value;

the IMD is further operable to communicate the patient therapy information to the external computing device; and

the external computing device comprises a patient communication interface operable to provide the patient therapy information to the patient.

6. The system as recited in claim 2, wherein:

the IMD comprises a processor operable to generate patient therapy information based at least in part on the relative physiologic parameter value;

the IMD is further operable to communicate the patient therapy information to the external computing device; and

the external computing device is operable to communicate the patient therapy information to the backend computing system for access by one or more health care providers.

7. The system as recited in claim 1, wherein the backend computing system comprises a database accessible by one or more health care providers, and wherein the one or more health care providers can obtain the relative physiologic parameter value from the database and use the relative physiologic parameter value to provide a service to the patient selected from the group consisting of diagnosing the patient, prescribing medication to the patient, providing a therapy to the patient, or modifying one or more settings of the IMD.

8. The system as recited in claim 1, wherein the absolute physiologic parameter value comprises blood pressure, wherein the ambient condition value comprises an ambient pressure value, and wherein the relative physiologic parameter value comprises the blood pressure value relative to the ambient pressure value.

9. The system as recited in claim 8, wherein the blood pressure is intravascular or intracardiac blood pressure.

10. The system as recited in claim 1, wherein the external computing device comprises an IMD programmer.

11. The system as recited in claim 1, wherein the external computing device comprises a repeater device in communication with the backend computing system.

12. The system as recited in claim 1, wherein the IMD and the external computing device are operable to communicate via a wireless communication connection selected from the group consisting of:

a radio frequency communication connection;

an acoustic communication connection;

an electrical field communication connection; and

an optical communication connection.

13. The system as recited in claim 1, wherein the IMD is selected from the group consisting of a physiologic parameter sensor, a pacemaker, a defibrillator, a bi-ventricular pacer, a ventricular assist blood pump, a drug delivery pump, a drug infusion device, a neurostimulating device, an intra-ocular shunt, and an intra-cranial shunt.

14. The system as recited in claim 1, wherein the backend computing system is operable to determine a therapy to provide to a patient, and wherein the backend computing system uses the relative physiologic parameter value to determine the therapy, the backend computing system further being operable to store the therapy information for access by one or more health care providers.

15. A method for deriving relative physiologic measurement values, comprising:

determining an absolute physiologic parameter value within a patient'"'"'s body with an implantable medical device (“

IMD”

), the IMD including a main body with a receiver in acoustic communication with a remote sensor system, the remote sensor system including a transmitter adapted to acoustically communicate the absolute physiologic parameter value to the receiver;

measuring the absolute physiologic parameter value with the remote sensor system and acoustically communicating the absolute physiologic parameter value to the receiver of the IMD;

communicating the absolute physiologic parameter value to an external computing device outside the patient'"'"'s body, the external computing device comprising a single device including communication circuitry configured to wirelessly receive the absolute physiologic parameter value and an integral sensor configured to sense an ambient condition value outside of the patient'"'"'s body;

sensing, via the sensor, an ambient condition value outside of the patient'"'"'s body related to the absolute physiologic parameter value;

communicating the absolute physiologic parameter value and the ambient condition value from the external computing device to a backend computing system;

calculating a relative physiologic parameter value from the ambient condition value and the absolute physiologic parameter value; and

storing the relative physiologic parameter value in a memory.

16. The method as recited in claim 15, further comprising the steps of:

communicating the relative physiologic parameter value to the external computing device with the backend computing system; and

storing the relative physiologic parameter value with the external computing device.

17. The method as recited in claim 16, further comprising the steps of:

communicating the relative physiologic parameter value to the IMD; and

storing the relative physiologic parameter value in a memory.

18. The method as recited in claim 17, wherein the steps of communicating the measured absolute physiologic parameter value to the external computing device and communicating the relative physiologic parameter value from the external computing device to the IMD comprise communicating via a wireless communication connection selected from the group consisting of:

a radio frequency communication connection;

an acoustic communication connection;

an electric field communication connection; and

an optical communication connection.

19. The method as recited in claim 17, further comprising:

determining a therapy to provide to the patient using the relative physiologic parameter value; and

providing the therapy to the patient with the IMD.

20. The method as recited in claim 19, wherein the therapy is selected from the group consisting of cardiac pacing therapy, anti-tachycardia therapy, drug delivery therapy, neurostimulation therapy, and blood pump therapy.

21. The method as recited in claim 17, further comprising:

generating patient therapy information with the IMD based at least in part on the relative physiologic parameter value;

communicating the patient therapy information from the IMD to the external computing device; and

providing the patient therapy information to the patient with the external computing device via a communication interface.

22. The method as recited in claim 17, further comprising:

generating patient therapy information with the IMD based at least in part on the relative physiologic parameter value;

communicating the patient therapy information from the IMD to the external computing device; and

communicating the patient therapy information to the backend computing system for access by one or more health care providers.

23. The method as recited in claim 15, further comprising the steps of:

storing the relative physiologic parameter value in a database of the backend computing system accessible by one or more health care providers obtaining the relative physiologic parameter value from the database; and

using the relative physiologic parameter value to provide a service to the patient selected from the group consisting of diagnosing the patient, prescribing medication to the patient, providing a therapy to the patient, or modifying one or more settings of the IMD.

24. The method as recited in claim 15, wherein the absolute physiologic parameter value comprises blood pressure, wherein the ambient condition value comprises an ambient pressure value, and wherein the relative physiologic parameter value comprises the blood pressure value relative to the ambient pressure value.

25. The method as recited in claim 24, wherein the blood pressure is intravascular or intracardiac blood pressure.

26. The method as recited in claim 15, wherein the step of obtaining an ambient condition value comprises the external computing device measuring the ambient condition value and communicating the ambient condition value to the backend computing system.

27. The method as recited in claim 15, wherein the external computing device comprises an IMD programmer.

28. The method as recited in claim 15, wherein the external computing device comprises a repeater device in communication with the backend computing system.

29. The method as recited in claim 15, wherein the IMD is selected from the group consisting of a physiologic parameter sensor, a pacemaker, a defibrillator, a bi-ventricular pacer, a ventricular assist blood pump, a drug delivery pump, a drug infusion device, a neurostimulating device, an intra-ocular shunt, and an intra-cranial shunt.

30. The method as recited in claim 15, further comprising:

determining a therapy to provide to a patient using the relative physiologic parameter value; and

storing the therapy information for access by one or more health care providers using the backend computing system.

31. A system for deriving relative blood pressure values, comprising:

an implantable medical device (“

IMD”

) including;

a remote sensor system adapted to be implanted in a patient'"'"'s body and operable to measure an internal blood pressure value, the remote sensor system including an acoustic transmitter;

a main body adapted to be implanted in the patient'"'"'s body, the main body including a receiver in acoustic communication with the transmitter of the remote sensor system and operable to acoustically receive the internal blood pressure value from the remote sensor system, the main body operable to communicate the internal blood pressure value outside the patient'"'"'s body;

an external computing device operable to;

wirelessly receive the internal blood pressure value from the IMD; and

communicate the internal blood pressure value to a backend computing system; and

the backend computing system operable to;

receive the internal blood pressure value from the external computing device;

obtain an ambient pressure value from an external monitor located outside the patient'"'"'s body;

calculate a relative blood pressure value from the ambient pressure value and the internal blood pressure value; and

store the calculated relative blood pressure value.

32. The system as recited in claim 31, wherein the backend computing system comprises a database accessible by one or more health care providers, and wherein the one or more health care providers can obtain the relative physiologic parameter value from the database and use the relative physiologic parameter value to provide a service to the patient selected from the group consisting of diagnosing the patient, prescribing medication to the patient, providing a therapy to the patient, or modifying one or more settings of the IMD.