Identifying heart failure patients suitable for resynchronization therapy using QRS complex width from an intracardiac electrogram
First Claim
1. A system comprising:
- a module providing an intrinsic atrio-ventricular delay of a patient and information for a QRS interval for the patient, the QRS interval occurring between the beginning of the intrinsic ventricular depolarization and the ending of the intrinsic ventricular depolarization, wherein the information for the QRS interval is indicative of whether a wide QRS interval is present in the QRS interval for the patient; and
a heart stimulation device, coupled to the module providing the intrinsic atrio-ventricular delay for the patient and information for the QRS interval for the patient, the heart stimulation device configured to set a paced atrio-ventricular delay to be substantially less than the intrinsic atrio-ventricular delay of the patient when the wide QRS interval is present.
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Abstract
Methods and systems are disclosed for determining whether a patient is a responder to cardiac resynchronization therapy. The beginning and ending of the intrinsic ventricular depolarization are determined through signals measured from one or more electrodes implanted in the patient'"'"'s heart. An interval between the beginning and ending of the intrinsic ventricular depolarization is computed and is compared to a threshold. The threshold may be determined empirically. The pacing parameters of a heart stimulation device, such as a pacemaker, may then be configured, for example, by setting the paced atrio-ventricular delay based on whether the patient responds positively to cardiac resynchronization therapy.
44 Citations
20 Claims
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1. A system comprising:
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a module providing an intrinsic atrio-ventricular delay of a patient and information for a QRS interval for the patient, the QRS interval occurring between the beginning of the intrinsic ventricular depolarization and the ending of the intrinsic ventricular depolarization, wherein the information for the QRS interval is indicative of whether a wide QRS interval is present in the QRS interval for the patient; and a heart stimulation device, coupled to the module providing the intrinsic atrio-ventricular delay for the patient and information for the QRS interval for the patient, the heart stimulation device configured to set a paced atrio-ventricular delay to be substantially less than the intrinsic atrio-ventricular delay of the patient when the wide QRS interval is present. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A system comprising:
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means for providing an intrinsic atrio-ventricular delay of a patient and information for a QRS interval for the patient, the QRS interval occurring between the beginning of the intrinsic ventricular depolarization and the ending of the intrinsic ventricular depolarization, wherein the information for the QRS interval for the patient is indicative of whether a wide QRS interval is present in the QRS interval for the patient; means for setting a paced atrio-ventricular delay to be substantially less than the intrinsic atrio-ventricular delay of the patient when the wide QRS interval is present. - View Dependent Claims (14, 15, 16)
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17. A method comprising:
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obtaining an intrinsic atrio-ventricular delay of a patient; obtaining information for a QRS interval for the patient, wherein the information for the QRS interval is indicative of whether a wide QRS interval, between a beginning of an intrinsic ventricular depolarization and an ending of the intrinsic ventricular depolarization, is present in the patient; and setting a paced atrio-ventricular delay of the patient to be substantially less than the intrinsic atrio-ventricular delay of the patient when the wide QRS interval is present in the patient. - View Dependent Claims (18, 19, 20)
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Specification