Autoantibody enhanced immunoassays and kits
First Claim
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1. A kit for detecting or quantifying an analyte of interest in a test sample, the kit comprising:
- a) a solid phase capable of binding autoantibodies present in the test sample;
b) a first antibody that binds to at least one epitope on the analyte of interest, the first antibody bound to the solid phase;
c) a second antibody that binds to at least one epitope on the analyte of interest; and
d) instructions for detecting or quantifying the analyte of interest.
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Abstract
The present disclosure provides immunoassays and kits for detection or quantification of an analyte of interest in a test sample that potentially contains endogenously produced autoantibodies reactive with the analyte.
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14 Claims
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1. A kit for detecting or quantifying an analyte of interest in a test sample, the kit comprising:
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a) a solid phase capable of binding autoantibodies present in the test sample; b) a first antibody that binds to at least one epitope on the analyte of interest, the first antibody bound to the solid phase; c) a second antibody that binds to at least one epitope on the analyte of interest; and d) instructions for detecting or quantifying the analyte of interest. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification