Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient

• US 8,317,858 B2
• Filed: 02/25/2009
• Issued: 11/27/2012
• Est. Priority Date: 02/26/2008
• Status: Active Grant

• Current Assignee: JenaValve Technology, Inc.
• Original Assignee: JenaValve Technology, Inc.
• Inventors: Straubinger, Helmut, Jung, Johannes
• Primary Examiner(s): Sweet, Thomas J
• Assistant Examiner(s): STEWART, JASON-DENNIS NEILKEN
• Application Number:
  US12/392,467
• Publication Number:
  US 20090216312A1
• Time in Patent Office: 1,371 Days
• Field of Search: 623/1.24, 623 211- 218, 623/1.15, 623/1.26
• US Class Current: 623/2.12
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0023 triangular
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2240/008 Means for testing implantable prostheses

Abstract

The present invention relates to a stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis fastened to a stent will occur relative the stent in the implanted state of the stent, even given the peristaltic motion of the heart, the stent according to the invention comprises at least one fastening portion via which the valvular prosthesis is connectable to the stent. The stent further comprises positioning arches and retaining arches, whereby at least one positioning arch is connected to at least one retaining arch via a first connecting web. The stent moreover comprises at least one auxiliary retaining arch which connects the respective arms of the at least one retaining arch connected to the at least one positioning arch.

Claims

1. An expandable stent, comprising:

a plurality of positioning arches, each having an apex projecting toward a proximal end of the stent, the plurality of positioning arches being configured to be positioned within a plurality of pockets of a native heart valve radially outward of a plurality of native heart valve leaflets,

a plurality of retaining arms, each having a proximal end, the plurality of retaining arms being configured to be positioned radially inward of the plurality of native heart valve leaflets, and

a first annular collar having a distal end connected to a proximal end of at least one of the plurality of retaining arms and a proximal end defining a proximalmost end of the stent,

wherein the proximal ends of the plurality of retaining arms are positioned closer to the proximalmost end of the stent than the proximal end of the plurality of positioning arches.

2. The expandable stent according to claim 1, wherein each of the plurality of positioning arches includes a substantially U-shaped or V-shaped structure.

3. The expandable stent according to claim 1, wherein the first annular collar includes a substantially lattice structure.

4. The expandable stent according to claim 1, further including a collapsed mode when being introduced into a patient'"'"'s body and an expanded mode when implanted.

5. The expandable stent according to claim 1, further including at least one radial arch substantially circumferentially aligned with at least one of the plurality of positioning arches, wherein the at least one radial arch includes first and second arms joined to one another at a radiused head portion.

6. The expandable stent according to claim 5, wherein the at least one radial arch includes a plurality of radial arches.

7. The expandable stent according to claim 1, further including a second annular collar.

8. The expandable stent according to claim 7, wherein the second annular collar is positioned at a distal end of the stent.

9. The expandable stent according to claim 7, wherein the second annular collar includes a substantially lattice structure.

10. An expandable stent, comprising:

a plurality of positioning arches configured to be positioned within a plurality of pockets of a native heart valve radially outward of a plurality of leaflets of the native valve, a plurality of retaining arches configured to support a heart valve prosthesis, and a first annular collar having a substantially lattice structure,

wherein each retaining arch is associated with a corresponding positioning arch and has a distal end portion axially aligned, along a longitudinal direction of the stent, with and joined to a distal end portion of the corresponding positioning arch, and

wherein the heart valve prosthesis is attached to the plurality of retaining arches such that at least part of the prosthetic valve extends from the plurality of retaining arches transversely across an interior of the stent.

11. The expandable stent according to claim 10, further including a collapsed mode when being introduced into a patient'"'"'s body and an expanded mode when implanted.

12. The expandable stent according to claim 10, wherein the plurality of positioning arches includes only three arches.

13. The expandable stent according to claim 10, further including a second annular collar having a substantially lattice structure, wherein the first annular collar is positioned at a distal end of the stent and the second annular collar is positioned at a proximal end of the stent.

14. An expandable stent comprising:

a plurality of positioning arches configured to be positioned within a plurality of pockets of a native heart valve, each of the plurality of positioning arches having an apex projecting toward a proximal end of the stent;

a plurality of retaining arms configured to support a heart valve prosthesis;

at least one strut member, interspaced between two adjacent positioning arches, the at least one strut member including a first end connected to at least one of the plurality of positioning arches, a second cantilevered end projecting toward the proximal end of the stent, and a plurality of fastening holes configured to receive a suture; and

a collar connected to each of the plurality of retaining arms.

15. The expandable stent according to claim 14, wherein the at least one strut member further includes a plurality of notches configured to anchor a suture.

16. The expandable stent according to claim 14, wherein the at least one strut member is a plurality of strut members, each strut member circumferentially interspaced between two adjacent positioning arches.

17. The expandable stent according to claim 14, wherein a valvular prosthesis is connected to the stent via at least one suture guided through at least a portion of the plurality of fastening holes.

18. The expandable stent according to claim 17, wherein the valvular prosthesis is made from pericardium.

19. The expandable stent according to claim 14, further including at least one radial arch interspaced between two adjacent positioning arches.

20. The expandable stent according to claim 14, wherein the collar includes a substantially lattice structure.