Method and system for providing integrated medication infusion and analyte monitoring system

• US 8,343,092 B2
• Filed: 11/24/2009
• Issued: 01/01/2013
• Est. Priority Date: 03/21/2005
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Rush, Benjamin M., Reggiardo, Christopher V.
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): Hall, Deanna K
• Application Number:
  US12/625,518
• Publication Number:
  US 20100076412A1
• Time in Patent Office: 1,134 Days
• Field of Search: 604/65, 604/66, 604/503, 604/504
• US Class Current: 604/65
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/6848 Needles
• CPC Class Codes: A61K 9/0009 involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis microelectromechanical systems A61K9/0097
• CPC Class Codes: A61K 9/0019 Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner non-active ingredients are additionally classified in A61K47/00
• CPC Class Codes: A61M 2005/1726 the body parameters being measured at, or proximate to, the infusion site
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

Method and system for integrating infusion device and analyte monitoring system including medication infusion device such as an insulin pump and an analyte monitoring system such as a glucose monitoring system are provided.

Claims

1. A glucose monitoring device, comprising:

a device housing including a display for outputting one or more of a graphical information or alphanumeric information;

a data communication connection provided in the housing including one or more of a wired communication section or a wireless communication section;

a strip port coupled to the housing and configured to receive an in vitro test strip; and

a controller operatively coupled to the data communication connection and the strip port and provided in the device housing, the controller configured to determine a blood glucose level based on a blood sample on the test strip, the controller further configured to process analyte sensor data corresponding to a monitored analyte level;

wherein the determined blood glucose level or the processed analyte sensor data or both, are output on the display graphically or alphanumerically or based on a combination thereof; and

further

wherein the controller is in signal communication with an on-body patch pump via the data communication connection and includes a memory having instructions stored which, when executed by one or more processors, causes the on-body patch pump to deliver a medication based on the delivery profile, wherein the delivery profile includes a plurality of predetermined discrete medication infusions temporally separated by a predetermined time period, and wherein the memory having instructions stored which, when executed by the processor, obtains at least one of the plurality of signals associated with the monitored analyte level substantially immediately prior to the delivery of each of the predetermined discrete medication infusions.

2. The device of claim 1 wherein the wired communication section includes a Universal Serial Bus (USB) connection physically coupled to the device housing, and configured to establish wired data communication to a data processing terminal.

3. The device of claim 2 wherein the determined blood glucose level or the processed analyte sensor data or both are transferred to the data processing terminal based on the USB connection.

4. The device of claim 1 wherein the analyte sensor data is received using the wireless communication section.

5. The device of claim 4 wherein the wireless communication section includes a radio frequency (RF) communication section.

6. The device of claim 1 wherein the controller is configured to communicate with an infusion device via the data communication connection.

7. The device of claim 6 wherein the controller transmits one or more signals to the infusion device to control the delivery rate of a fluid based on the one or more analyte sensor data.

8. The device of claim 7 wherein the fluid is insulin.

9. The device of claim 1 wherein the analyte sensor data includes analyte sensor data received from an in vivo glucose sensor.

10. The device of claim 1 including an input unit provided on the housing to enter one or more input commands to the device.

11. The device of claim 10 wherein the input unit includes one or more of a button or a jog dial.

12. The device of claim 1 wherein the controller is further configured to determine a medication dose.

13. The device of claim 12 wherein the controller is configured to execute the determined medication dose.

14. The device of claim 12 wherein the controller is configured to determine the medication dose based at least in part on the determined blood glucose level or the processed analyte sensor data or both.

15. The device of claim 12 wherein the medication dose is output on the display graphically or alphanumerically or based on a combination thereof.

16. The device of claim 12 wherein the medication dose includes a bolus dose.

17. The device of claim 16 wherein the bolus dose includes a correction bolus, a carbohydrate bolus, an extended bolus, a dual bolus, or one or more combinations thereof.

18. The device of claim 12 wherein the controller determines the medication dose based on one or more of an insulin sensitivity information, insulin on board information, intended carbohydrate intake information, measured glucose level, detected glucose level, or glucose trend information.

19. A device, comprising:

a device housing including a display for outputting one or more of a graphical information or alphanumeric information;

a data communication connection provided in the housing including one or more of a wired communication section or a wireless communication section;

a strip port coupled to the housing and configured to receive an in vitro test strip; and

a controller operatively coupled to the data communication connection and the strip port and provided in the device housing, the controller configured to determine a blood glucose level based on a blood sample on the test strip and to process analyte sensor data corresponding to a monitored analyte level, the controller further configured to determine a medication dose based at least in part on one or more of the determined blood glucose level or the processed analyte sensor data;

wherein one or more of the determined blood glucose level, the processed analyte sensor data, or the determined medication dose, are output on the display graphically or alphanumerically or based on a combination thereof;

wherein the graphical output on the display includes an analyte level trend information; and

further

wherein the controller is in signal communication with an on-body patch pump via the data communication connection and includes a memory having instructions stored which, when executed by one or more processors, causes the on-body patch pump to deliver a medication based on the delivery profile, wherein the delivery profile includes a plurality of predetermined discrete medication infusions temporally separated by a predetermined time period, and wherein the memory having instructions stored which, when executed by the processor, obtains at least one of the plurality of signals associated with the monitored analyte level substantially immediately prior to the delivery of each of the predetermined discrete medication infusions.

20. The device of claim 19 wherein the wired communication section includes a Universal Serial Bus (USB) connection physically coupled to the device housing, and configured to establish wired data communication to a data processing terminal.

21. The device of claim 20 wherein the determined blood glucose level or the processed analyte sensor data or both are transferred to the data processing terminal based on the USB connection.

22. The device of claim 19 wherein the analyte sensor data is received using the wireless communication section.

23. The device of claim 22 wherein the wireless communication section includes a radio frequency (RF) communication section.

24. The device of claim 19 wherein the controller is configured to communicate with an infusion device via the data communication connection.

25. The device of claim 24 wherein the controller transmits one or more signals to the infusion device to control the delivery rate of a fluid based on the one or more analyte sensor data.

26. The device of claim 25 wherein the delivery rate of the fluid is related to the determined medication dose.

27. The device of claim 25 wherein the fluid is insulin.

28. The device of claim 19 wherein the analyte sensor data includes analyte sensor data received from an in vivo glucose sensor.

29. The device of claim 19 including an input unit provided on the housing to enter one or more input commands to the device.

30. The device of claim 29 wherein the input unit includes one or more of a button or a jog dial.

31. The device of claim 19 wherein the controller is configured to execute the determined medication dose.

32. The device of claim 19 wherein the medication dose includes a bolus dose.

33. The device of claim 32 wherein the bolus dose includes a correction bolus, a carbohydrate bolus, an extended bolus, a dual bolus, or one or more combinations thereof.

34. The device of claim 19 wherein the controller determines the medication dose based on one or more of an insulin sensitivity information, insulin on board information, intended carbohydrate intake information, measured glucose level, detected glucose level, or glucose trend information.