Liquid formulations of bendamustine

  • US 8,344,006 B2
  • Filed: 01/31/2012
  • Issued: 01/01/2013
  • Est. Priority Date: 09/25/2008
  • Status: Active Grant
First Claim
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1. A stable, non-aqueous liquid, pharmaceutical formulation comprising from about 5 mg/ml to about 120 mg/mL of bendamustine, or a pharmaceutically acceptable salt thereof, solubilized in about 66% (v/v) of dimethylacetamide and about 34% (v/v) of propylene glycol, wherein said formulation, following dilution with a pharmaceutically acceptable diluent, is suitable for injection into a patient without lyophilization.

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