Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise

  • US 8,364,229 B2
  • Filed: 05/18/2007
  • Issued: 01/29/2013
  • Est. Priority Date: 07/25/2003
  • Status: Active Grant
First Claim
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1. A diffusion-based glucose sensor, comprising:

  • an electrode configured to detect a signal related to a glucose concentration of a host; and

    a membrane comprising a silicone-hydrophilic polymer blend configured to decrease diffusion of at least one interferent to the electrode, whereby a signal component related to the at least one interferent is less than 20% of the signal for at least one day in vivo, wherein the silicone-hydrophilic polymer blend is configured to slow diffusion of reactive oxygen and nitrogen interferents therethrough.

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