Systems, devices, and methods including infection-fighting and monitoring shunts
First Claim
Patent Images
1. An implantable shunt system, comprising:
- one or more fluid-flow passageways configured to receive a cerebrospinal fluid of a biological subject;
one or more energy emitters configured to emit an energy stimulus of a character and for a time sufficient to induce apoptosis without substantially inducing necrosis of at least a portion of cells within a cerebrospinal fluid received within at least one of the one or more fluid-flow passageways;
one or more sensors configured to detect at least one characteristic associated with the cerebrospinal fluid of the biological subject; and
one or more computer-readable memory media having cerebrospinal fluid information configured as a data structure, the data structure including at least one of infection indication information, inflammation indication information, diseased state indication information, and diseased tissue indication information.
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Accused Products
Abstract
Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
224 Citations
42 Claims
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1. An implantable shunt system, comprising:
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one or more fluid-flow passageways configured to receive a cerebrospinal fluid of a biological subject; one or more energy emitters configured to emit an energy stimulus of a character and for a time sufficient to induce apoptosis without substantially inducing necrosis of at least a portion of cells within a cerebrospinal fluid received within at least one of the one or more fluid-flow passageways; one or more sensors configured to detect at least one characteristic associated with the cerebrospinal fluid of the biological subject; and one or more computer-readable memory media having cerebrospinal fluid information configured as a data structure, the data structure including at least one of infection indication information, inflammation indication information, diseased state indication information, and diseased tissue indication information. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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39. An implantable shunt system, comprising:
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one or more fluid-flow passageways configured to receive a cerebrospinal fluid of a biological subject; and one or more energy emitters configured to emit an energy stimulus of a character and for a time sufficient to induce apoptosis without substantially inducing necrosis of at least a portion of cells within a cerebrospinal fluid received within at least one of the one or more fluid-flow passageways; wherein at least one of the one or more fluid-flow passageways includes a surface region that is energetically actuatable between an optically transparent state and an optically reflective state.
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40. An implantable shunt system, comprising:
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one or more fluid-flow passageways configured to receive a cerebrospinal fluid of a biological subject; and one or more energy emitters configured to emit an energy stimulus of a character and for a time sufficient to induce apoptosis without substantially inducing necrosis of at least a portion of cells within a cerebrospinal fluid received within at least one of the one or more fluid-flow passageways; wherein at least one of the one or more fluid-flow passageways includes one or more regions that are actively controllable between a transmissive state and a reflective state.
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41. An implantable shunt system, comprising:
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one or more fluid-flow passageways configured to receive a cerebrospinal fluid of a biological subject; one or more energy emitters configured to emit an energy stimulus of a character and for a time sufficient to induce apoptosis without substantially inducing necrosis of at least a portion of cells within a cerebrospinal fluid received within at least one of the one or more fluid-flow passageways; one or more sensors configured to detect at least one characteristic associated with the cerebrospinal fluid of the biological subject; and one or more computer-readable memory media having cerebrospinal fluid information configured as a data structure, the data structure including at least one of psychosis state marker information, psychosis trait marker information, and psychosis indication information.
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42. An implantable shunt system, comprising:
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one or more fluid-flow passageways configured to receive a cerebrospinal fluid of a biological subject; one or more energy emitters configured to emit an energy stimulus of a character and for a time sufficient to induce apoptosis without substantially inducing necrosis of at least a portion of cells within a cerebrospinal fluid received within at least one of the one or more fluid-flow passageways; and a power source, the power source including at least one of a thermoelectric generator, a piezoelectric generator, an electromechanical generator, and a biomechanical-energy harvesting generator.
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Specification