Therapeutic compositions

  • US 8,372,827 B2
  • Filed: 07/31/2012
  • Issued: 02/12/2013
  • Est. Priority Date: 12/16/2005
  • Status: Active Grant
First Claim
Patent Images

1. A pharmaceutical formulation for topical use in treatment of a subject, said pharmaceutical formulation comprising ingenol angelate in an amount from about 0.001% to about 0.15% w/w, wherein at least about 97.5% of the ingenol angelate is ingenol-3-angelate (isoform ‘

  • b’

    ) and said pharmaceutical formulation has a pH of less than 4.

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