Natural marine source phospholipids comprising polyunsaturated fatty acids and their applications

• US 8,383,675 B2
• Filed: 07/10/2012
• Issued: 02/26/2013
• Est. Priority Date: 07/27/2001
• Status: Expired due to Term

• Current Assignee: Aker BioMarine Antarctic AS (Aker BioMarine ASA), DTI Group BV
• Original Assignee: Neptune Technologies & Bioressources Incorporated (Quebec)
• Inventors: Sampalis, Fotini
• Primary Examiner(s): Lundgren, Jeffrey S
• Assistant Examiner(s): Polansky, Gregg
• Application Number:
  US13/545,830
• Publication Number:
  US 20120277196A1
• Time in Patent Office: 231 Days
• Field of Search: None
• US Class Current: 514/506
• CPC Class Codes: A23J 7/00 Phosphatide compositions for foodstuffs, e.g. lecithin
• CPC Class Codes: A23K 20/158 Fatty acids; Fats; Products containing oils or fats
• CPC Class Codes: A23L 33/115 Fatty acids or derivatives thereof; Fats or oils
• CPC Class Codes: A23L 33/30 Dietetic or nutritional methods, e.g. for losing weight A23L33/10 takes precedence
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2250/1846 Phosphatidyl Choline
• CPC Class Codes: A23V 2250/1848 Phosphatidyl Ethanolamine
• CPC Class Codes: A23V 2250/185 Phosphatidyl Inositol
• CPC Class Codes: A23V 2250/1852 Phosphatidyl Serine
• CPC Class Codes: A23V 2250/1868 Docosahexaenoic acid
• CPC Class Codes: A23V 2250/187 Eicosapentaenoic acid
• CPC Class Codes: A23V 2250/70 Vitamins
• CPC Class Codes: A61K 2800/522 Antioxidants; Radical scavengers
• CPC Class Codes: A61K 31/122 having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• CPC Class Codes: A61K 31/353 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• CPC Class Codes: A61K 31/661 Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
• CPC Class Codes: A61K 31/6615 Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
• CPC Class Codes: A61K 31/683 Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
• CPC Class Codes: A61K 31/685 one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
• CPC Class Codes: A61K 35/612 Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
• CPC Class Codes: A61K 8/553 : Phospholipids, e.g. lecithin
• CPC Class Codes: A61K 9/0053 : Mouth and digestive tract, i.e. intraoral and peroral administration rectal administration A61K9/0031
• CPC Class Codes: A61K 9/48 : Preparations in capsules, e.g. of gelatin, of chocolate A61K9/0004 takes precedence; bite capsules A61K9/0056
• CPC Class Codes: A61P 1/00 : Drugs for disorders of the alimentary tract or the digestive system
• CPC Class Codes: A61P 1/04 : for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
• CPC Class Codes: A61P 1/16 : for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• CPC Class Codes: A61P 13/12 : of the kidneys
• CPC Class Codes: A61P 17/00 : Drugs for dermatological disorders
• CPC Class Codes: A61P 25/00 : Drugs for disorders of the nervous system
• CPC Class Codes: A61P 25/16 : Anti-Parkinson drugs
• CPC Class Codes: A61P 25/28 : for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• CPC Class Codes: A61P 25/32 : Alcohol-abuse
• CPC Class Codes: A61P 3/00 : Drugs for disorders of the metabolism of the blood or the extracellular fluid A61P7/00
• CPC Class Codes: A61P 3/06 : Antihyperlipidemics
• CPC Class Codes: A61P 35/00 : Antineoplastic agents
• CPC Class Codes: A61P 9/00 : Drugs for disorders of the cardiovascular system
• CPC Class Codes: A61P 9/12 : Antihypertensives
• CPC Class Codes: A61Q 19/00 : Preparations for care of the skin
• CPC Class Codes: C07D 407/14 : containing three or more hetero rings
• CPC Class Codes: C07F 9/10 : Phosphatides, e.g. lecithin
• CPC Class Codes: C07F 9/117 : with cycloaliphatic alcohols
• CPC Class Codes: C11B 1/10 : by extracting

Abstract

A phospholipid extract from a marine or aquatic biomass possesses therapeutic properties. The phospholipid extract comprises a variety of phospholipids, fatty acid, metals and a novel flavonoid.

Claims

1. A capsule comprising an Antarctic krill oil extract comprising a phospholipid of the formula (I),