Acetylcysteine composition and uses thereof

  • US 8,399,445 B2
  • Filed: 02/27/2012
  • Issued: 03/19/2013
  • Est. Priority Date: 08/24/2005
  • Status: Active Grant
First Claim
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1. A method of treating acetaminophen overdose, comprising:

  • using a stable aqueous pharmaceutical composition comprising 200 mg/ml acetylcysteine or pharmaceutically acceptable salts thereof, wherein the composition is free of chelating agents, wherein said composition is in a suitable form for intravenous injection, wherein the pH of the composition is from 6 to 7.5, and wherein said composition is sealed in an airtight container comprising a fill volume of said composition and a headspace volume occupied by a pharmaceutically inert gas;

    diluting the composition in an aqueous solution; and

    administering the diluted composition to a patient in need thereof.

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